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Evidence for Recombinant GRP78, CALR, PDIA3 and GPI as Mediators of Genetic Instability in Human CD34+ Cells

SIMPLE SUMMARY: Factors secreted from irradiated mesenchymal stromal cells (MSC) may exert genotoxic effects in human CD34+ cells, thereby potentially contributing to the pathogenesis of hematologic disorders such as leukemias. In a proteomics approach, we recently identified four key proteins in th...

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Detalles Bibliográficos
Autores principales: Fabarius, Alice, Samra, Vanessa, Drews, Oliver, Mörz, Handan, Bierbaum, Miriam, Darwich, Ali, Weiss, Christel, Brendel, Susanne, Kleiner, Helga, Seifarth, Wolfgang, Greffrath, Wolfgang, Hofmann, Wolf-Karsten, Schmitt, Clemens A., Popp, Henning D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221337/
https://www.ncbi.nlm.nih.gov/pubmed/35740549
http://dx.doi.org/10.3390/cancers14122883