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Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent

Coronary artery disease is one of the most common diseases in developed countries and affects a large part of the population of developing countries. Preventing restenosis in patients with implanted stents is an important current medical problem. The purpose of this work is to analyse the viability...

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Autores principales: Rodríguez, Antonio, Barroso, Pablo, Olmo, Alberto, Yúfera, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221340/
https://www.ncbi.nlm.nih.gov/pubmed/35735563
http://dx.doi.org/10.3390/bios12060416
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author Rodríguez, Antonio
Barroso, Pablo
Olmo, Alberto
Yúfera, Alberto
author_facet Rodríguez, Antonio
Barroso, Pablo
Olmo, Alberto
Yúfera, Alberto
author_sort Rodríguez, Antonio
collection PubMed
description Coronary artery disease is one of the most common diseases in developed countries and affects a large part of the population of developing countries. Preventing restenosis in patients with implanted stents is an important current medical problem. The purpose of this work is to analyse the viability of bioimpedance sensing to detect the formation of atheromatous plaque in an implantable stent. Simulations in COMSOL Multiphysics were performed to analyse the performance of the proposed bioimpedance sensing system, based on the Sheffield technique. Both non-pathological and pathological models (with atheromatous plaque), including the flow of blood were considered. Simulations with the non-pathological model showed a homogeneous distribution of the measured current intensity in the different electrodes, for every configuration. On the other hand, simulations with the pathological model showed a significant decrease of the measured current intensity in the electrodes close to the simulated atheromatous plaque. The presence of the atheromatous plaque can, therefore, be detected by the system with a simple algorithm, avoiding the full reconstruction of the image and the subsequent computational processing requirements.
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spelling pubmed-92213402022-06-24 Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent Rodríguez, Antonio Barroso, Pablo Olmo, Alberto Yúfera, Alberto Biosensors (Basel) Communication Coronary artery disease is one of the most common diseases in developed countries and affects a large part of the population of developing countries. Preventing restenosis in patients with implanted stents is an important current medical problem. The purpose of this work is to analyse the viability of bioimpedance sensing to detect the formation of atheromatous plaque in an implantable stent. Simulations in COMSOL Multiphysics were performed to analyse the performance of the proposed bioimpedance sensing system, based on the Sheffield technique. Both non-pathological and pathological models (with atheromatous plaque), including the flow of blood were considered. Simulations with the non-pathological model showed a homogeneous distribution of the measured current intensity in the different electrodes, for every configuration. On the other hand, simulations with the pathological model showed a significant decrease of the measured current intensity in the electrodes close to the simulated atheromatous plaque. The presence of the atheromatous plaque can, therefore, be detected by the system with a simple algorithm, avoiding the full reconstruction of the image and the subsequent computational processing requirements. MDPI 2022-06-15 /pmc/articles/PMC9221340/ /pubmed/35735563 http://dx.doi.org/10.3390/bios12060416 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Rodríguez, Antonio
Barroso, Pablo
Olmo, Alberto
Yúfera, Alberto
Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent
title Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent
title_full Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent
title_fullStr Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent
title_full_unstemmed Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent
title_short Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent
title_sort bioimpedance sensing of implanted stent occlusions: smart stent
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221340/
https://www.ncbi.nlm.nih.gov/pubmed/35735563
http://dx.doi.org/10.3390/bios12060416
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