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Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent
Coronary artery disease is one of the most common diseases in developed countries and affects a large part of the population of developing countries. Preventing restenosis in patients with implanted stents is an important current medical problem. The purpose of this work is to analyse the viability...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221340/ https://www.ncbi.nlm.nih.gov/pubmed/35735563 http://dx.doi.org/10.3390/bios12060416 |
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author | Rodríguez, Antonio Barroso, Pablo Olmo, Alberto Yúfera, Alberto |
author_facet | Rodríguez, Antonio Barroso, Pablo Olmo, Alberto Yúfera, Alberto |
author_sort | Rodríguez, Antonio |
collection | PubMed |
description | Coronary artery disease is one of the most common diseases in developed countries and affects a large part of the population of developing countries. Preventing restenosis in patients with implanted stents is an important current medical problem. The purpose of this work is to analyse the viability of bioimpedance sensing to detect the formation of atheromatous plaque in an implantable stent. Simulations in COMSOL Multiphysics were performed to analyse the performance of the proposed bioimpedance sensing system, based on the Sheffield technique. Both non-pathological and pathological models (with atheromatous plaque), including the flow of blood were considered. Simulations with the non-pathological model showed a homogeneous distribution of the measured current intensity in the different electrodes, for every configuration. On the other hand, simulations with the pathological model showed a significant decrease of the measured current intensity in the electrodes close to the simulated atheromatous plaque. The presence of the atheromatous plaque can, therefore, be detected by the system with a simple algorithm, avoiding the full reconstruction of the image and the subsequent computational processing requirements. |
format | Online Article Text |
id | pubmed-9221340 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92213402022-06-24 Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent Rodríguez, Antonio Barroso, Pablo Olmo, Alberto Yúfera, Alberto Biosensors (Basel) Communication Coronary artery disease is one of the most common diseases in developed countries and affects a large part of the population of developing countries. Preventing restenosis in patients with implanted stents is an important current medical problem. The purpose of this work is to analyse the viability of bioimpedance sensing to detect the formation of atheromatous plaque in an implantable stent. Simulations in COMSOL Multiphysics were performed to analyse the performance of the proposed bioimpedance sensing system, based on the Sheffield technique. Both non-pathological and pathological models (with atheromatous plaque), including the flow of blood were considered. Simulations with the non-pathological model showed a homogeneous distribution of the measured current intensity in the different electrodes, for every configuration. On the other hand, simulations with the pathological model showed a significant decrease of the measured current intensity in the electrodes close to the simulated atheromatous plaque. The presence of the atheromatous plaque can, therefore, be detected by the system with a simple algorithm, avoiding the full reconstruction of the image and the subsequent computational processing requirements. MDPI 2022-06-15 /pmc/articles/PMC9221340/ /pubmed/35735563 http://dx.doi.org/10.3390/bios12060416 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Rodríguez, Antonio Barroso, Pablo Olmo, Alberto Yúfera, Alberto Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent |
title | Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent |
title_full | Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent |
title_fullStr | Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent |
title_full_unstemmed | Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent |
title_short | Bioimpedance Sensing of Implanted Stent Occlusions: Smart Stent |
title_sort | bioimpedance sensing of implanted stent occlusions: smart stent |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221340/ https://www.ncbi.nlm.nih.gov/pubmed/35735563 http://dx.doi.org/10.3390/bios12060416 |
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