Cargando…

IFI35 Promotes Renal Cancer Progression by Inhibiting pSTAT1/pSTAT6-Dependent Autophagy

SIMPLE SUMMARY: Interferon-induced protein 35 (IFI35) plays an important role in virus-related immune inflammatory responses. However, the biological significance and function of IFI35 in cancer is still not well understood. Our goal is to explore whether IFI35 could be used as tumor marker or a the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chai, Dafei, Shi, Shang Yuchen, Sobhani, Navid, Ding, Jiage, Zhang, Zichun, Jiang, Nan, Wang, Gang, Li, Minle, Li, Hailong, Zheng, Junnian, Bai, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221357/ https://www.ncbi.nlm.nih.gov/pubmed/35740527 http://dx.doi.org/10.3390/cancers14122861

Ejemplares similares

Expression of tSTAT3, pSTAT3(727), and pSTAT3 (705) in the epithelial cells of hormone‐naïve prostate cancer
por: Krzyzanowska, Agnieszka, et al.
Publicado: (2019)

Direct targets of pSTAT5 signalling in erythropoiesis
por: Gillinder, Kevin R., et al.
Publicado: (2017)

Potential Refinement of Recurrence Score by pSTAT3 Status
por: Grinshpun, Albert, et al.
Publicado: (2022)

pSTAT1 Is Activated during the Progression of IgA Nephropathy
por: Tao, Jianling, et al.
Publicado: (2022)

Prognostic Significance of B-Cells and pSTAT3 in Patients with Ovarian Cancer
por: Yang, Chunmei, et al.
Publicado: (2013)

The assessment of correlation and prognosis among (18)F-FDG uptake parameters, Glut1, pStat1 and pStat3 in surgically resected non-small cell lung cancer patients
por: Kaida, Hayato, et al.
Publicado: (2018)

Inhibition of pSTAT1 by tofacitinib accounts for the early improvement of experimental chronic synovitis
por: Pérez-Baos, Sandra, et al.
Publicado: (2019)

Dynamic Changes in pStat3 Are Involved in Meiotic Spindle Assembly in Mouse Oocytes
por: Haraguchi, Seiki, et al.
Publicado: (2020)

Adiponectin receptor agonists inhibit leptin induced pSTAT3 and in vivo pancreatic tumor growth
por: Messaggio, Fanuel, et al.
Publicado: (2017)

Impaired T-bet-pSTAT1α and perforin-mediated immune responses in the tumoral region of lung adenocarcinoma
por: Andreev, Katerina, et al.
Publicado: (2015)

Impaired T-bet-pSTAT1α and perforin-mediated immune responses in the tumoral region of lung adenocarcinoma
por: Andreev, Katerina, et al.
Publicado: (2016)

IL-6-Driven pSTAT1 Response Is Linked to T Cell Features Implicated in Early Immune Dysregulation
por: Lambert, Katharina, et al.
Publicado: (2022)

Gemcitabine enhances cell invasion via activating HAb18G/CD147-EGFR-pSTAT3 signaling
por: Xu, Bao-Qing, et al.
Publicado: (2016)

Immunohistochemical Features of MMP-9 and pSTAT1 in Granuloma Annulare and Sarcoidosis: A Comparative Study of 62 Cases
por: Wu, Ze, et al.
Publicado: (2023)

The clinical significance and underlying correlation of pStat-3 and integrin αvβ6 expression in gallbladder cancer
por: Enyu, Liu, et al.
Publicado: (2017)

Formononetin Inhibits Progression of Endometriosis via Regulation of p27, pSTAT3, and Progesterone Receptor: In Vitro and In Vivo Studies
por: Park, Yunjeong, et al.
Publicado: (2023)

AXL-initiated paracrine activation of pSTAT3 enhances mesenchymal and vasculogenic supportive features of tumor-associated macrophages
por: Hung, Chia-Nung, et al.
Publicado: (2023)

pSTAT3 Levels Have Divergent Expression Patterns and Associations with Survival in Squamous Cell Carcinoma and Adenocarcinoma of the Oesophagus
por: O’ Sullivan, Katie E., et al.
Publicado: (2018)

Phosphorylated transducer and activator of transcription-3 (pSTAT3) immunohistochemical expression in paired primary and metastatic colorectal cancer
por: Marginean, Esmeralda C., et al.
Publicado: (2020)

BSCI-10. Invasive growth of brain metastases is driven by cancer cell-pSTAT3+ reactive astrocyte crosstalk
por: Dankner, Matthew, et al.
Publicado: (2021)

Molecular targets for anticancer redox chemotherapy and cisplatin-induced ototoxicity: the role of curcumin on pSTAT3 and Nrf-2 signalling
por: Fetoni, A R, et al.
Publicado: (2015)

Homocysteine induces mitochondrial dysfunction involving the crosstalk between oxidative stress and mitochondrial pSTAT3 in rat ischemic brain
por: Chen, Shuang, et al.
Publicado: (2017)

Mouse Microglial Calcitonin Receptor Knockout Impairs Hypothalamic Amylin Neuronal pSTAT3 Signaling but Lacks Major Metabolic Consequences
por: Coester, Bernd, et al.
Publicado: (2022)

Sorafenib with ASC‐J9(®) synergistically suppresses the HCC progression via altering the pSTAT3‐CCL2/Bcl2 signals
por: Xu, Junjie, et al.
Publicado: (2016)

pSTAT3: a target biomarker to study the pharmacology of the anti-IL-21R antibody ATR-107 in human whole blood
por: Zhu, Ming, et al.
Publicado: (2013)

TLR4 and pSTAT3 Expression on Circulating Tumor Cells (CTCs) and Immune Cells in the Peripheral Blood of Breast Cancer Patients: Prognostic Implications
por: Papadaki, Maria A., et al.
Publicado: (2022)

Effect of plant produced Anti-hIL-6 receptor antibody blockade on pSTAT3 expression in human peripheral blood mononuclear cells
por: Kaewbandit, Namthip, et al.
Publicado: (2023)

NF-κB and pSTAT3 synergistically drive G6PD overexpression and facilitate sensitivity to G6PD inhibition in ccRCC
por: Zhang, Qiao, et al.
Publicado: (2020)

Tumor suppressor HIC1 is synergistically compromised by cancer-associated fibroblasts and tumor cells through the IL-6/pSTAT3 axis in breast cancer
por: Sun, Xueqing, et al.
Publicado: (2019)

A report on the potential of Rac1/pSTAT3 protein levels in T lymphocytes to assess the pharmacodynamic effect of thiopurine therapy in Inflammatory Bowel Disease patients
por: Deben, Debbie S., et al.
Publicado: (2022)

Folic acid deficiency exacerbates the inflammatory response of astrocytes after ischemia‐reperfusion by enhancing the interaction between IL‐6 and JAK‐1/pSTAT3
por: Cheng, Man, et al.
Publicado: (2023)

Antiproliferative and Anti-invasion Effects of Carvacrol on PC3 Human Prostate Cancer Cells through Reducing pSTAT3, pAKT, and pERK1/2 Signaling Proteins
por: Heidarian, Esfandiar, et al.
Publicado: (2019)

Correction to: NF-κB and pSTAT3 synergistically drive G6PD overexpression and facilitate sensitivity to G6PD inhibition in ccRCC
por: Zhang, Qiao, et al.
Publicado: (2020)

Author Correction: Effect of plant produced Anti-hIL-6 receptor antibody blockade on pSTAT3 expression in human peripheral blood mononuclear cells
por: Kaewbandit, Namthip, et al.
Publicado: (2023)

Mesenchymal stromal cells-derived extracellular vesicles reprogramme macrophages in ARDS models through the miR-181a-5p-PTEN-pSTAT5-SOCS1 axis
por: Su, Yue, et al.
Publicado: (2023)

Increased expression of the Th17-IL-6R/pSTAT3/BATF/RorγT-axis in the tumoural region of adenocarcinoma as compared to squamous cell carcinoma of the lung
por: Balabko, Ljubov, et al.
Publicado: (2014)

Increasing AR by HIF-2α inhibitor (PT-2385) overcomes the side-effects of sorafenib by suppressing hepatocellular carcinoma invasion via alteration of pSTAT3, pAKT and pERK signals
por: Xu, Junjie, et al.
Publicado: (2017)

The psoriasis-protective TYK2 I684S variant impairs IL-12 stimulated pSTAT4 response in skin-homing CD4+ and CD8+ memory T-cells
por: Enerbäck, C., et al.
Publicado: (2018)

The co-delivery of adenovirus-based immune checkpoint vaccine elicits a potent anti-tumor effect in renal carcinoma
por: Jiang, Nan, et al.
Publicado: (2023)

HMGB1/GPC3 dual targeting vaccine induces dendritic cells-mediated CD8(+)T cell immune response and elicits potential therapeutic effect in hepatocellular carcinoma
por: Shi, Xiaoqing, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_smeut93tj4sfalq203svmautg7