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Transcriptomic Profiling Reveals That HMGB1 Induces Macrophage Polarization Different from Classical M1

Macrophages are key inflammatory immune cells that display dynamic phenotypes and functions in response to their local microenvironment. In different conditions, macrophage polarization can be induced by high-mobility group box 1 (HMGB1), a nuclear DNA-binding protein that activates innate immunity...

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Detalles Bibliográficos
Autores principales: Qu, Heshuang, Heinbäck, Rebecka, Salo, Henna, Ewing, Ewoud, Espinosa, Alexander, Aulin, Cecilia, Erlandsson Harris, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221381/
https://www.ncbi.nlm.nih.gov/pubmed/35740904
http://dx.doi.org/10.3390/biom12060779