Molecular Detection of Venous Thrombosis in Mouse Models Using SPECT/CT

The efficacy of thrombolysis is inversely correlated with thrombus age. During early thrombogenesis, activated factor XIII (FXIIIa) cross-links [Formula: see text] 2-AP to fibrin to protect it from early lysis. This was exploited to develop an [Formula: see text] 2-AP-based imaging agent to detect e...

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Detalles Bibliográficos
Autores principales: Dickhout, Annemiek, Van de Vijver, Pieter, Bitsch, Nicole, van Hoof, Stefan J., Thomassen, Stella L. G. D., Massberg, Steffen, Timmerman, Peter, Verhaegen, Frank, Koenen, Rory R., Dijkgraaf, Ingrid, Hackeng, Tilman M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221411/
https://www.ncbi.nlm.nih.gov/pubmed/35740954
http://dx.doi.org/10.3390/biom12060829

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