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Immunogenicity of Novel AAV Capsids for Retinal Gene Therapy

Objectives: AAV vectors are widely used in gene therapy, but the prevalence of neutralizing antibodies raised against AAV serotypes in the course of a natural infection, as well as innate and adaptive immune responses induced upon vector administration, is still considered an important limitation. I...

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Detalles Bibliográficos
Autores principales:	Gehrke, Miranda, Diedrichs-Möhring, Maria, Bogedein, Jacqueline, Büning, Hildegard, Michalakis, Stylianos, Wildner, Gerhild
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221425/ https://www.ncbi.nlm.nih.gov/pubmed/35741009 http://dx.doi.org/10.3390/cells11121881

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