Targeting Acid Ceramidase Inhibits Glioblastoma Cell Migration through Decreased AKT Signaling

Glioblastoma (GBM) remains one of the most aggressive cancers, partially due to its ability to migrate into the surrounding brain. The sphingolipid balance, or the balance between ceramides and sphingosine-1-phosphate, contributes to the ability of GBM cells to migrate or invade. Of the ceramidases...

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Detalles Bibliográficos
Autores principales: Hawkins, Cyntanna C., Jones, Amber B., Gordon, Emily R., Williford, Sarah E., Harsh, Yuvika, Ziebro, Julia K., Landis, Catherine J., Gc, Sajina, Crossman, David K., Cooper, Sara J., Ramanadham, Sasanka, Doan, Ninh, Hjelmeland, Anita B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221433/
https://www.ncbi.nlm.nih.gov/pubmed/35741006
http://dx.doi.org/10.3390/cells11121873

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