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Peptidomimetics Based on C-Terminus of Blm10 Stimulate Human 20S Proteasome Activity and Promote Degradation of Proteins

Degradation of misfolded, redundant and oxidatively damaged proteins constitutes one of the cellular processes which are influenced by the 20S proteasome. However, its activity is generally thought to decrease with age which leads to the gradual accumulation of abnormal proteins in cells and their s...

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Detalles Bibliográficos
Autores principales: Cekała, Katarzyna, Trepczyk, Karolina, Sowik, Daria, Karpowicz, Przemysław, Giełdoń, Artur, Witkowska, Julia, Giżyńska, Małgorzata, Jankowska, Elżbieta, Wieczerzak, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221443/
https://www.ncbi.nlm.nih.gov/pubmed/35740902
http://dx.doi.org/10.3390/biom12060777