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Therapeutic Vulnerability to ATR Inhibition in Concurrent NF1 and ATRX-Deficient/ALT-Positive High-Grade Solid Tumors

SIMPLE SUMMARY: Tumors of the brain and nerves develop frequently in patients with neurofibromatosis type 1. Many are benign growths, such as pilocytic astrocytomas in the brain and neurofibromas in the nerves. However, in some patients, the tumors become malignant and may cause local damage, dissem...

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Detalles Bibliográficos
Autores principales:	Yuan, Ming, Eberhart, Charles G., Pratilas, Christine A., Blakeley, Jaishri O., Davis, Christine, Stojanova, Marija, Reilly, Karlyne, Meeker, Alan K., Heaphy, Christopher M., Rodriguez, Fausto J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221513/ https://www.ncbi.nlm.nih.gov/pubmed/35740680 http://dx.doi.org/10.3390/cancers14123015

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