Super-Resolution Imaging of Fas/CD95 Reorganization Induced by Membrane-Bound Fas Ligand Reveals Nanoscale Clustering Upstream of FADD Recruitment

Signaling through the TNF-family receptor Fas/CD95 can trigger apoptosis or non-apoptotic cellular responses and is essential for protection from autoimmunity. Receptor clustering has been observed following interaction with Fas ligand (FasL), but the stoichiometry of Fas, particularly when triggere...

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Detalles Bibliográficos
Autores principales: Frazzette, Nicholas, Cruz, Anthony C., Wu, Xufeng, Hammer, John A., Lippincott-Schwartz, Jennifer, Siegel, Richard M., Sengupta, Prabuddha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221696/
https://www.ncbi.nlm.nih.gov/pubmed/35741037
http://dx.doi.org/10.3390/cells11121908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221696/
https://www.ncbi.nlm.nih.gov/pubmed/35741037
http://dx.doi.org/10.3390/cells11121908

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