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Low-Dose High-Resolution Photon-Counting CT of the Lung: Radiation Dose and Image Quality in the Clinical Routine

This study aims to investigate the qualitative and quantitative image quality of low-dose high-resolution (LD-HR) lung CT scans acquired with the first clinical approved photon counting CT (PCCT) scanner. Furthermore, the radiation dose used by the PCCT is compared to a conventional CT scanner with...

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Autores principales: Woeltjen, Matthias Michael, Niehoff, Julius Henning, Michael, Arwed Elias, Horstmeier, Sebastian, Moenninghoff, Christoph, Borggrefe, Jan, Kroeger, Jan Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221815/
https://www.ncbi.nlm.nih.gov/pubmed/35741251
http://dx.doi.org/10.3390/diagnostics12061441
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author Woeltjen, Matthias Michael
Niehoff, Julius Henning
Michael, Arwed Elias
Horstmeier, Sebastian
Moenninghoff, Christoph
Borggrefe, Jan
Kroeger, Jan Robert
author_facet Woeltjen, Matthias Michael
Niehoff, Julius Henning
Michael, Arwed Elias
Horstmeier, Sebastian
Moenninghoff, Christoph
Borggrefe, Jan
Kroeger, Jan Robert
author_sort Woeltjen, Matthias Michael
collection PubMed
description This study aims to investigate the qualitative and quantitative image quality of low-dose high-resolution (LD-HR) lung CT scans acquired with the first clinical approved photon counting CT (PCCT) scanner. Furthermore, the radiation dose used by the PCCT is compared to a conventional CT scanner with an energy-integrating detector system (EID-CT). Twenty-nine patients who underwent a LD-HR chest CT scan with dual-source PCCT and had previously undergone a LD-HR chest CT with a standard EID-CT scanner were retrospectively included in this study. Images of the whole lung as well as enlarged image sections displaying a specific finding (lesion) were evaluated in terms of overall image quality, image sharpness and image noise by three senior radiologists using a 5-point Likert scale. The PCCT images were reconstructed with and without a quantum iterative reconstruction algorithm (PCCT QIR+/−). Noise and signal-to-noise (SNR) were measured and the effective radiation dose was calculated. Overall, image quality and image sharpness were rated best in PCCT (QIR+) images. A significant difference was seen particularly in image sections of PCCT (QIR+) images compared to EID-CT images (p < 0.005). Image noise of PCCT (QIR+) images was significantly lower compared to EID-CT images in image sections (p = 0.005). In contrast, noise was lowest on EID-CT images (p < 0.001). The PCCT used significantly less radiation dose compared to the EID-CT (p < 0.001). In conclusion, LD-HR PCCT scans of the lung provide better image quality while using significantly less radiation dose compared to EID-CT scans.
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spelling pubmed-92218152022-06-24 Low-Dose High-Resolution Photon-Counting CT of the Lung: Radiation Dose and Image Quality in the Clinical Routine Woeltjen, Matthias Michael Niehoff, Julius Henning Michael, Arwed Elias Horstmeier, Sebastian Moenninghoff, Christoph Borggrefe, Jan Kroeger, Jan Robert Diagnostics (Basel) Article This study aims to investigate the qualitative and quantitative image quality of low-dose high-resolution (LD-HR) lung CT scans acquired with the first clinical approved photon counting CT (PCCT) scanner. Furthermore, the radiation dose used by the PCCT is compared to a conventional CT scanner with an energy-integrating detector system (EID-CT). Twenty-nine patients who underwent a LD-HR chest CT scan with dual-source PCCT and had previously undergone a LD-HR chest CT with a standard EID-CT scanner were retrospectively included in this study. Images of the whole lung as well as enlarged image sections displaying a specific finding (lesion) were evaluated in terms of overall image quality, image sharpness and image noise by three senior radiologists using a 5-point Likert scale. The PCCT images were reconstructed with and without a quantum iterative reconstruction algorithm (PCCT QIR+/−). Noise and signal-to-noise (SNR) were measured and the effective radiation dose was calculated. Overall, image quality and image sharpness were rated best in PCCT (QIR+) images. A significant difference was seen particularly in image sections of PCCT (QIR+) images compared to EID-CT images (p < 0.005). Image noise of PCCT (QIR+) images was significantly lower compared to EID-CT images in image sections (p = 0.005). In contrast, noise was lowest on EID-CT images (p < 0.001). The PCCT used significantly less radiation dose compared to the EID-CT (p < 0.001). In conclusion, LD-HR PCCT scans of the lung provide better image quality while using significantly less radiation dose compared to EID-CT scans. MDPI 2022-06-11 /pmc/articles/PMC9221815/ /pubmed/35741251 http://dx.doi.org/10.3390/diagnostics12061441 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Woeltjen, Matthias Michael
Niehoff, Julius Henning
Michael, Arwed Elias
Horstmeier, Sebastian
Moenninghoff, Christoph
Borggrefe, Jan
Kroeger, Jan Robert
Low-Dose High-Resolution Photon-Counting CT of the Lung: Radiation Dose and Image Quality in the Clinical Routine
title Low-Dose High-Resolution Photon-Counting CT of the Lung: Radiation Dose and Image Quality in the Clinical Routine
title_full Low-Dose High-Resolution Photon-Counting CT of the Lung: Radiation Dose and Image Quality in the Clinical Routine
title_fullStr Low-Dose High-Resolution Photon-Counting CT of the Lung: Radiation Dose and Image Quality in the Clinical Routine
title_full_unstemmed Low-Dose High-Resolution Photon-Counting CT of the Lung: Radiation Dose and Image Quality in the Clinical Routine
title_short Low-Dose High-Resolution Photon-Counting CT of the Lung: Radiation Dose and Image Quality in the Clinical Routine
title_sort low-dose high-resolution photon-counting ct of the lung: radiation dose and image quality in the clinical routine
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221815/
https://www.ncbi.nlm.nih.gov/pubmed/35741251
http://dx.doi.org/10.3390/diagnostics12061441
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