Challenges in Cell Fate Acquisition to Scid-Repopulating Activity from Hemogenic Endothelium of hiPSCs Derived from AML Patients Using Forced Transcription Factor Expression

The generation of human hematopoietic stem cells (HSCs) from human pluripotent stem cells (hPSCs) represents a major goal in regenerative medicine and is believed would follow principles of early development. HSCs arise from a type of endothelial cell called a “hemogenic endothelium” (HE), and human...

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Detalles Bibliográficos
Autores principales: Porras, Deanna P., Reid, Jennifer C., Tanasijevic, Borko, Golubeva, Diana, Boyd, Allison L., Bhatia, Mickie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221973/
https://www.ncbi.nlm.nih.gov/pubmed/35741044
http://dx.doi.org/10.3390/cells11121915

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