Cargando…
Schwannoma of the Upper Limb: Retrospective Study of a Rare Tumor with Uncommon Locations
Background: Although schwannoma (neurilemmoma) is the most common tumor of the peripheral nerve, its low incidence, slow growth and vague symptoms often lead to misdiagnosis or delayed diagnosis. The aim of the study is to present a series with a large number of schwannomas in the upper limbs, some...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222006/ https://www.ncbi.nlm.nih.gov/pubmed/35741129 http://dx.doi.org/10.3390/diagnostics12061319 |
_version_ | 1784732766852612096 |
---|---|
author | Pertea, Mihaela Filip, Alexandru Huzum, Bogdan Lunca, Sorinel Carp, Claudiu Mitrea, Mihaela Toader, Paula Luca, Stefana Moraru, Dan Cristian Poroch, Vladimir Veliceasa, Bogdan |
author_facet | Pertea, Mihaela Filip, Alexandru Huzum, Bogdan Lunca, Sorinel Carp, Claudiu Mitrea, Mihaela Toader, Paula Luca, Stefana Moraru, Dan Cristian Poroch, Vladimir Veliceasa, Bogdan |
author_sort | Pertea, Mihaela |
collection | PubMed |
description | Background: Although schwannoma (neurilemmoma) is the most common tumor of the peripheral nerve, its low incidence, slow growth and vague symptoms often lead to misdiagnosis or delayed diagnosis. The aim of the study is to present a series with a large number of schwannomas in the upper limbs, some with very rare occurrence. Methods: We report 17 patients with a mean age of 58.5 years and upper limb schwannomas, located on the median, ulnar and radial nerves, but also on the posterior interosseous nerve and digital collateral nerves. The diagnosis was made by clinical examination and imaging tests, and in no case was a preoperative biopsy performed. Surgical treatment was established based on symptoms or aesthetic concerns. In all cases, a diagnosis of schwannoma was confirmed through histopathological and immunohistochemical examinations. Results: For all patients, a complete tumor enucleation was performed under a surgical microscope. No recurrence was recorded at 2 years after surgery. Patient satisfaction was good, with complete socio-professional integration in all cases. Conclusions: Although more frequently present on the main nerve trunks, schwannoma may be present on the collateral digital nerves in rare cases. A correct technique with complete tumor excision offers excellent postoperative outcomes and avoids recurrences. |
format | Online Article Text |
id | pubmed-9222006 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92220062022-06-24 Schwannoma of the Upper Limb: Retrospective Study of a Rare Tumor with Uncommon Locations Pertea, Mihaela Filip, Alexandru Huzum, Bogdan Lunca, Sorinel Carp, Claudiu Mitrea, Mihaela Toader, Paula Luca, Stefana Moraru, Dan Cristian Poroch, Vladimir Veliceasa, Bogdan Diagnostics (Basel) Article Background: Although schwannoma (neurilemmoma) is the most common tumor of the peripheral nerve, its low incidence, slow growth and vague symptoms often lead to misdiagnosis or delayed diagnosis. The aim of the study is to present a series with a large number of schwannomas in the upper limbs, some with very rare occurrence. Methods: We report 17 patients with a mean age of 58.5 years and upper limb schwannomas, located on the median, ulnar and radial nerves, but also on the posterior interosseous nerve and digital collateral nerves. The diagnosis was made by clinical examination and imaging tests, and in no case was a preoperative biopsy performed. Surgical treatment was established based on symptoms or aesthetic concerns. In all cases, a diagnosis of schwannoma was confirmed through histopathological and immunohistochemical examinations. Results: For all patients, a complete tumor enucleation was performed under a surgical microscope. No recurrence was recorded at 2 years after surgery. Patient satisfaction was good, with complete socio-professional integration in all cases. Conclusions: Although more frequently present on the main nerve trunks, schwannoma may be present on the collateral digital nerves in rare cases. A correct technique with complete tumor excision offers excellent postoperative outcomes and avoids recurrences. MDPI 2022-05-26 /pmc/articles/PMC9222006/ /pubmed/35741129 http://dx.doi.org/10.3390/diagnostics12061319 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Pertea, Mihaela Filip, Alexandru Huzum, Bogdan Lunca, Sorinel Carp, Claudiu Mitrea, Mihaela Toader, Paula Luca, Stefana Moraru, Dan Cristian Poroch, Vladimir Veliceasa, Bogdan Schwannoma of the Upper Limb: Retrospective Study of a Rare Tumor with Uncommon Locations |
title | Schwannoma of the Upper Limb: Retrospective Study of a Rare Tumor with Uncommon Locations |
title_full | Schwannoma of the Upper Limb: Retrospective Study of a Rare Tumor with Uncommon Locations |
title_fullStr | Schwannoma of the Upper Limb: Retrospective Study of a Rare Tumor with Uncommon Locations |
title_full_unstemmed | Schwannoma of the Upper Limb: Retrospective Study of a Rare Tumor with Uncommon Locations |
title_short | Schwannoma of the Upper Limb: Retrospective Study of a Rare Tumor with Uncommon Locations |
title_sort | schwannoma of the upper limb: retrospective study of a rare tumor with uncommon locations |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222006/ https://www.ncbi.nlm.nih.gov/pubmed/35741129 http://dx.doi.org/10.3390/diagnostics12061319 |
work_keys_str_mv | AT perteamihaela schwannomaoftheupperlimbretrospectivestudyofararetumorwithuncommonlocations AT filipalexandru schwannomaoftheupperlimbretrospectivestudyofararetumorwithuncommonlocations AT huzumbogdan schwannomaoftheupperlimbretrospectivestudyofararetumorwithuncommonlocations AT luncasorinel schwannomaoftheupperlimbretrospectivestudyofararetumorwithuncommonlocations AT carpclaudiu schwannomaoftheupperlimbretrospectivestudyofararetumorwithuncommonlocations AT mitreamihaela schwannomaoftheupperlimbretrospectivestudyofararetumorwithuncommonlocations AT toaderpaula schwannomaoftheupperlimbretrospectivestudyofararetumorwithuncommonlocations AT lucastefana schwannomaoftheupperlimbretrospectivestudyofararetumorwithuncommonlocations AT morarudancristian schwannomaoftheupperlimbretrospectivestudyofararetumorwithuncommonlocations AT porochvladimir schwannomaoftheupperlimbretrospectivestudyofararetumorwithuncommonlocations AT veliceasabogdan schwannomaoftheupperlimbretrospectivestudyofararetumorwithuncommonlocations |