Efficacy and Safety of Granulocyte-Colony Stimulating Factor Therapy in Chagas Cardiomyopathy: A Phase II Double-Blind, Randomized, Placebo-Controlled Clinical Trial

AIM: Previous studies showed that granulocyte-colony stimulating factor (G-CSF) improved heart function in a mice model of Chronic Chagas Cardiomyopathy (CCC). Herein, we report the interim results of the safety and efficacy of G-CSF therapy vs. placebo in adults with Chagas cardiomyopathy. METHODS:...

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Detalles Bibliográficos
Autores principales: Macedo, Carolina T., Larocca, Ticiana F., Noya-Rabelo, Márcia, Aras, Roque, Macedo, Cristiano R. B., Moreira, Moisés I., Caldas, Alessandra C., Torreão, Jorge A., Monsão, Victor M. A., Souza, Clarissa L. M., Vasconcelos, Juliana F., Bezerra, Milena R., Petri, Daniela P., Souza, Bruno S. F., Pacheco, Antônio G. F., Daher, André, Ribeiro-dos-Santos, Ricardo, Soares, Milena B. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222127/
https://www.ncbi.nlm.nih.gov/pubmed/35757326
http://dx.doi.org/10.3389/fcvm.2022.864837

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