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A Robust Assay to Monitor Ataxin-3 Amyloid Fibril Assembly

Spinocerebellar ataxia type 3 (SCA3) is caused by the expansion of a glutamine repeat in the protein ataxin-3, which is deposited as intracellular aggregates in affected brain regions. Despite the controversial role of ataxin-3 amyloid structures in SCA3 pathology, the identification of molecules wi...

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Detalles Bibliográficos
Autores principales:	Figueiredo, Francisco, Lopes-Marques, Mónica, Almeida, Bruno, Matscheko, Nena, Martins, Pedro M., Silva, Alexandra, Macedo-Ribeiro, Sandra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222203/ https://www.ncbi.nlm.nih.gov/pubmed/35741099 http://dx.doi.org/10.3390/cells11121969

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