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Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture

The functionalization of self-assembled peptide hydrogel is of great importance to broaden its applications in the field of biomedicine. In this work, conductive hydrogel is fabricated by introducing conductive polymer polyaniline into peptide self-assembled hydrogel. Compared with pure peptide form...

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Detalles Bibliográficos
Autores principales: Li, Jieling, Xue, Yan, Wang, Anhe, Tian, Shaonan, Li, Qi, Bai, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222261/
https://www.ncbi.nlm.nih.gov/pubmed/35735716
http://dx.doi.org/10.3390/gels8060372
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author Li, Jieling
Xue, Yan
Wang, Anhe
Tian, Shaonan
Li, Qi
Bai, Shuo
author_facet Li, Jieling
Xue, Yan
Wang, Anhe
Tian, Shaonan
Li, Qi
Bai, Shuo
author_sort Li, Jieling
collection PubMed
description The functionalization of self-assembled peptide hydrogel is of great importance to broaden its applications in the field of biomedicine. In this work, conductive hydrogel is fabricated by introducing conductive polymer polyaniline into peptide self-assembled hydrogel. Compared with pure peptide formed hydrogel, the conductive hydrogel exhibits enhanced conductivity, mechanical property and stability. In addition, the hydrogel is tested to be of great injectability and 3D bio-printability and could support the viability of encapsulated cells that are sensitive to electrical signals. It should have great application prospects in the preparation of tissue engineering scaffolds.
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spelling pubmed-92222612022-06-24 Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture Li, Jieling Xue, Yan Wang, Anhe Tian, Shaonan Li, Qi Bai, Shuo Gels Article The functionalization of self-assembled peptide hydrogel is of great importance to broaden its applications in the field of biomedicine. In this work, conductive hydrogel is fabricated by introducing conductive polymer polyaniline into peptide self-assembled hydrogel. Compared with pure peptide formed hydrogel, the conductive hydrogel exhibits enhanced conductivity, mechanical property and stability. In addition, the hydrogel is tested to be of great injectability and 3D bio-printability and could support the viability of encapsulated cells that are sensitive to electrical signals. It should have great application prospects in the preparation of tissue engineering scaffolds. MDPI 2022-06-13 /pmc/articles/PMC9222261/ /pubmed/35735716 http://dx.doi.org/10.3390/gels8060372 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Li, Jieling
Xue, Yan
Wang, Anhe
Tian, Shaonan
Li, Qi
Bai, Shuo
Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture
title Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture
title_full Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture
title_fullStr Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture
title_full_unstemmed Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture
title_short Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture
title_sort polyaniline functionalized peptide self-assembled conductive hydrogel for 3d cell culture
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222261/
https://www.ncbi.nlm.nih.gov/pubmed/35735716
http://dx.doi.org/10.3390/gels8060372
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AT tianshaonan polyanilinefunctionalizedpeptideselfassembledconductivehydrogelfor3dcellculture
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