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Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture
The functionalization of self-assembled peptide hydrogel is of great importance to broaden its applications in the field of biomedicine. In this work, conductive hydrogel is fabricated by introducing conductive polymer polyaniline into peptide self-assembled hydrogel. Compared with pure peptide form...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222261/ https://www.ncbi.nlm.nih.gov/pubmed/35735716 http://dx.doi.org/10.3390/gels8060372 |
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author | Li, Jieling Xue, Yan Wang, Anhe Tian, Shaonan Li, Qi Bai, Shuo |
author_facet | Li, Jieling Xue, Yan Wang, Anhe Tian, Shaonan Li, Qi Bai, Shuo |
author_sort | Li, Jieling |
collection | PubMed |
description | The functionalization of self-assembled peptide hydrogel is of great importance to broaden its applications in the field of biomedicine. In this work, conductive hydrogel is fabricated by introducing conductive polymer polyaniline into peptide self-assembled hydrogel. Compared with pure peptide formed hydrogel, the conductive hydrogel exhibits enhanced conductivity, mechanical property and stability. In addition, the hydrogel is tested to be of great injectability and 3D bio-printability and could support the viability of encapsulated cells that are sensitive to electrical signals. It should have great application prospects in the preparation of tissue engineering scaffolds. |
format | Online Article Text |
id | pubmed-9222261 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-92222612022-06-24 Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture Li, Jieling Xue, Yan Wang, Anhe Tian, Shaonan Li, Qi Bai, Shuo Gels Article The functionalization of self-assembled peptide hydrogel is of great importance to broaden its applications in the field of biomedicine. In this work, conductive hydrogel is fabricated by introducing conductive polymer polyaniline into peptide self-assembled hydrogel. Compared with pure peptide formed hydrogel, the conductive hydrogel exhibits enhanced conductivity, mechanical property and stability. In addition, the hydrogel is tested to be of great injectability and 3D bio-printability and could support the viability of encapsulated cells that are sensitive to electrical signals. It should have great application prospects in the preparation of tissue engineering scaffolds. MDPI 2022-06-13 /pmc/articles/PMC9222261/ /pubmed/35735716 http://dx.doi.org/10.3390/gels8060372 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Li, Jieling Xue, Yan Wang, Anhe Tian, Shaonan Li, Qi Bai, Shuo Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture |
title | Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture |
title_full | Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture |
title_fullStr | Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture |
title_full_unstemmed | Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture |
title_short | Polyaniline Functionalized Peptide Self-Assembled Conductive Hydrogel for 3D Cell Culture |
title_sort | polyaniline functionalized peptide self-assembled conductive hydrogel for 3d cell culture |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222261/ https://www.ncbi.nlm.nih.gov/pubmed/35735716 http://dx.doi.org/10.3390/gels8060372 |
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