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Differential Nutrition-Health Properties of Ocimum basilicum Leaf and Stem Extracts

(1) Background: Ocimum basilicum L. is an aromatic medicinal plant of the Lamiaceae family known as sweet basil. It is used in traditional medicine for its beneficial effects on gastrointestinal disorders, inflammation, immune system, pyrexia or cancer among others. Ocimum basilicum (OB) leaf extrac...

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Autores principales: Bensaid, Aicha, Boudard, Frederic, Servent, Adrien, Morel, Sylvie, Portet, Karine, Guzman, Caroline, Vitou, Manon, Bichon, Florence, Poucheret, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222536/
https://www.ncbi.nlm.nih.gov/pubmed/35741897
http://dx.doi.org/10.3390/foods11121699
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author Bensaid, Aicha
Boudard, Frederic
Servent, Adrien
Morel, Sylvie
Portet, Karine
Guzman, Caroline
Vitou, Manon
Bichon, Florence
Poucheret, Patrick
author_facet Bensaid, Aicha
Boudard, Frederic
Servent, Adrien
Morel, Sylvie
Portet, Karine
Guzman, Caroline
Vitou, Manon
Bichon, Florence
Poucheret, Patrick
author_sort Bensaid, Aicha
collection PubMed
description (1) Background: Ocimum basilicum L. is an aromatic medicinal plant of the Lamiaceae family known as sweet basil. It is used in traditional medicine for its beneficial effects on gastrointestinal disorders, inflammation, immune system, pyrexia or cancer among others. Ocimum basilicum (OB) leaf extracts contain many phytochemicals bearing the plant health effects but no reports is available on the potential bioactivity of stem extracts. Our investigation aimed at assessing the differential biological activity between basil leaf and stem to promote this co-product valorization. (2) Method: For this purpose we explored phytochemical composition of both parts of the plant. Antioxidant activity was evaluated through total polyphenol content measure, DPPH and ORAC tests. Anti-inflammatory markers on stimulated macrophages, including NO (nitric oxide), TNFa (tumor necrosis factor alpha), IL-6 (interleukin 6), MCP1 (monocyte attractant protein 1) and PGE-2 (prostaglandin E2), were evaluated. In addition, we investigated OB effects on jejunum smooth muscle contractility. (3) Results: OB extracts from leaves and stems demonstrated a different biological activity profile at the level of both antioxidant, anti-inflammatory and smooth muscle relaxation effects. (4) Conclusion: Taken together our results suggest that Ocimum basilicum extracts from co-product stems, in addition to leaves, may be of interest at the nutrition-health level with specific therapeutic potential.
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spelling pubmed-92225362022-06-24 Differential Nutrition-Health Properties of Ocimum basilicum Leaf and Stem Extracts Bensaid, Aicha Boudard, Frederic Servent, Adrien Morel, Sylvie Portet, Karine Guzman, Caroline Vitou, Manon Bichon, Florence Poucheret, Patrick Foods Article (1) Background: Ocimum basilicum L. is an aromatic medicinal plant of the Lamiaceae family known as sweet basil. It is used in traditional medicine for its beneficial effects on gastrointestinal disorders, inflammation, immune system, pyrexia or cancer among others. Ocimum basilicum (OB) leaf extracts contain many phytochemicals bearing the plant health effects but no reports is available on the potential bioactivity of stem extracts. Our investigation aimed at assessing the differential biological activity between basil leaf and stem to promote this co-product valorization. (2) Method: For this purpose we explored phytochemical composition of both parts of the plant. Antioxidant activity was evaluated through total polyphenol content measure, DPPH and ORAC tests. Anti-inflammatory markers on stimulated macrophages, including NO (nitric oxide), TNFa (tumor necrosis factor alpha), IL-6 (interleukin 6), MCP1 (monocyte attractant protein 1) and PGE-2 (prostaglandin E2), were evaluated. In addition, we investigated OB effects on jejunum smooth muscle contractility. (3) Results: OB extracts from leaves and stems demonstrated a different biological activity profile at the level of both antioxidant, anti-inflammatory and smooth muscle relaxation effects. (4) Conclusion: Taken together our results suggest that Ocimum basilicum extracts from co-product stems, in addition to leaves, may be of interest at the nutrition-health level with specific therapeutic potential. MDPI 2022-06-09 /pmc/articles/PMC9222536/ /pubmed/35741897 http://dx.doi.org/10.3390/foods11121699 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bensaid, Aicha
Boudard, Frederic
Servent, Adrien
Morel, Sylvie
Portet, Karine
Guzman, Caroline
Vitou, Manon
Bichon, Florence
Poucheret, Patrick
Differential Nutrition-Health Properties of Ocimum basilicum Leaf and Stem Extracts
title Differential Nutrition-Health Properties of Ocimum basilicum Leaf and Stem Extracts
title_full Differential Nutrition-Health Properties of Ocimum basilicum Leaf and Stem Extracts
title_fullStr Differential Nutrition-Health Properties of Ocimum basilicum Leaf and Stem Extracts
title_full_unstemmed Differential Nutrition-Health Properties of Ocimum basilicum Leaf and Stem Extracts
title_short Differential Nutrition-Health Properties of Ocimum basilicum Leaf and Stem Extracts
title_sort differential nutrition-health properties of ocimum basilicum leaf and stem extracts
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222536/
https://www.ncbi.nlm.nih.gov/pubmed/35741897
http://dx.doi.org/10.3390/foods11121699
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