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Discovery and Functional Characterization of Two Regulatory Variants Underlying Lupus Susceptibility at 2p13.1
Genome-wide association studies have identified 2p13.1 as a prominent susceptibility locus for systemic lupus erythematosus (SLE)—a complex, multisystem autoimmune disease. However, the identity of underlying causal variant (s) and molecular mechanisms for increasing disease susceptibility are poorl...
Autores principales: | Fazel-Najafabadi, Mehdi, Rallabandi, Harikrishna-Reddy, Singh, Manish K., Maiti, Guru P., Morris, Jacqueline, Looger, Loren L., Nath, Swapan K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9222795/ https://www.ncbi.nlm.nih.gov/pubmed/35741778 http://dx.doi.org/10.3390/genes13061016 |
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