Cargando…

The polyol pathway is an evolutionarily conserved system for sensing glucose uptake

Cells must adjust the expression levels of metabolic enzymes in response to fluctuating nutrient supply. For glucose, such metabolic remodeling is highly dependent on a master transcription factor ChREBP/MondoA. However, it remains elusive how glucose fluctuations are sensed by ChREBP/MondoA despite...

Descripción completa

Detalles Bibliográficos
Autores principales: Sano, Hiroko, Nakamura, Akira, Yamane, Mariko, Niwa, Hitoshi, Nishimura, Takashi, Araki, Kimi, Takemoto, Kazumasa, Ishiguro, Kei-ichiro, Aoki, Hiroki, Kato, Yuzuru, Kojima, Masayasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223304/
https://www.ncbi.nlm.nih.gov/pubmed/35687590
http://dx.doi.org/10.1371/journal.pbio.3001678