Cargando…

Metabolomic Profiling of Angiotensin-II-Induced Abdominal Aortic Aneurysm in Ldlr(−/−) Mice Points to Alteration of Nitric Oxide, Lipid, and Energy Metabolisms

Aneurysm is the second-most common disease affecting the aorta worldwide after atherosclerosis. While several clinical metabolomic studies have been reported, no study has reported deep metabolomic phenotyping in experimental animal models of aortic aneurysm. We performed a targeted metabolomics stu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chao de la Barca, Juan Manuel, Richard, Alexis, Robert, Pauline, Eid, Maroua, Fouquet, Olivier, Tessier, Lydie, Wetterwald, Céline, Faure, Justine, Fassot, Celine, Henrion, Daniel, Reynier, Pascal, Loufrani, Laurent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223449/ https://www.ncbi.nlm.nih.gov/pubmed/35742839 http://dx.doi.org/10.3390/ijms23126387

Ejemplares similares

The AGE-Breaker ALT-711 Restores High Blood Flow–Dependent Remodeling in Mesenteric Resistance Arteries in a Rat Model of Type 2 Diabetes
por: Freidja, Mohamed L., et al.
Publicado: (2012)

Microvascular vasodilator properties of the angiotensin II type 2 receptor in a mouse model of type 1 diabetes
por: Begorre, Marc-Antoine, et al.
Publicado: (2017)

COX-2-Derived Prostanoids and Oxidative Stress Additionally Reduce Endothelium-Mediated Relaxation in Old Type 2 Diabetic Rats
por: Vessières, Emilie, et al.
Publicado: (2013)

Sildenafil-Induced Revascularization of Rat Hindlimb Involves Arteriogenesis through PI3K/AKT and eNOS Activation
por: Baron-Menguy, Celine, et al.
Publicado: (2022)

A Tear Metabolomic Profile Showing Increased Ornithine Decarboxylase Activity and Spermine Synthesis in Thyroid-Associated Orbitopathy
por: Billiet, Benjamin, et al.
Publicado: (2022)

Do storage solutions protect endothelial function of arterialized vein graft in an experimental rat model?
por: Fouquet, Olivier, et al.
Publicado: (2020)

Author’s reply (in reference to letter to editor proposed by Etem Caliskan, Catherine J. Pachuk, Louis P. Perrault, Maximilian Y Emmert and entitled: preservation solutions to improve graft patency: The devil is in the detail)
por: Fouquet, Olivier, et al.
Publicado: (2021)

In Utero Exposure to Maternal Diabetes Is Associated With Early Abnormal Vascular Structure in Offspring
por: Dib, Abdallah, et al.
Publicado: (2018)

AGEs breaking and antioxidant treatment improves endothelium-dependent dilation without effect on flow-mediated remodeling of resistance arteries in old Zucker diabetic rats
por: Freidja, Mohamed L, et al.
Publicado: (2014)

Long Lasting Microvascular Tone Alteration in Rat Offspring Exposed In Utero to Maternal Hyperglycaemia
por: Vessières, Emilie, et al.
Publicado: (2016)

Tributyrin Intake Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm in LDLR(-/-) Mice
por: Lin, Chih-Pei, et al.
Publicado: (2023)

The endothelial αENaC contributes to vascular endothelial function in vivo
por: Tarjus, Antoine, et al.
Publicado: (2017)

Dual Role of Thrombospondin-1 in Flow-Induced Remodeling
por: Grenier, Céline, et al.
Publicado: (2021)

Metabolomic Profiling of Plasma and Erythrocytes in Sickle Mice Points to Altered Nociceptive Pathways
por: Dembélé, Klétigui Casimir, et al.
Publicado: (2020)

Nuclear Activation Function 2 Estrogen Receptor α Attenuates Arterial and Renal Alterations Due to Aging and Hypertension in Female Mice
por: Guivarc'h, Emmanuel, et al.
Publicado: (2020)

Cardiopulmonary bypass and internal thoracic artery: Can roller or centrifugal pumps change vascular reactivity of the graft? The IPITA study: A randomized controlled clinical trial
por: Fouquet, Olivier, et al.
Publicado: (2020)

Retinal metabolic events in preconditioning light stress as revealed by wide-spectrum targeted metabolomics
por: de la Barca, Juan Manuel Chao, et al.
Publicado: (2017)

Triciribine increases LDLR expression and LDL uptake through stabilization of LDLR mRNA
por: Bjune, Katrine, et al.
Publicado: (2018)

MLb-LDLr: A Machine Learning Model for Predicting the Pathogenicity of LDLr Missense Variants
por: Larrea-Sebal, Asier, et al.
Publicado: (2021)

Increased Inflammation in Atherosclerotic Lesions of Diabetic Akita-LDLr (−/−) Mice Compared to Nondiabetic LDLr (−/−) Mice
por: Engelbertsen, Daniel, et al.
Publicado: (2012)

From Drought Sensing to Developmental Control: Evolution of Cyclic AMP Signaling in Social Amoebas
por: Ritchie, Allyson V., et al.
Publicado: (2008)

Increase in Cardiac Ischemia-Reperfusion Injuries in Opa1(+/-) Mouse Model
por: Le Page, Sophie, et al.
Publicado: (2016)

Oxidative Stress and Lipid Accumulation Augments Cell Death in LDLR-Deficient RPE Cells and Ldlr (−/−) Mice
por: Sreekumar, Parameswaran Gangadharan, et al.
Publicado: (2022)

The Beneficial Effect of Lomitapide on the Cardiovascular System in LDLr(−/−) Mice with Obesity
por: Munkhsaikhan, Undral, et al.
Publicado: (2023)

Primate-specific evolution of an LDLR enhancer
por: Wang, Qian-fei, et al.
Publicado: (2006)

T Cells in Atherosclerosis in Ldlr−/− and Apoe−/− Mice
por: Getz, Godfrey S., et al.
Publicado: (2018)

Therapeutic targets of hypercholesterolemia: HMGCR and LDLR
por: Ma, Shizhan, et al.
Publicado: (2019)

In Utero Exposure to Maternal Diabetes Impairs Vascular Expression of Prostacyclin Receptor in Rat Offspring
por: Van Huyen, Jean-Paul Duong, et al.
Publicado: (2010)

The enigma of soluble LDLR: could inflammation be the key?
por: Mbikay, Majambu, et al.
Publicado: (2020)

Validation of LDLr Activity as a Tool to Improve Genetic Diagnosis of Familial Hypercholesterolemia: A Retrospective on Functional Characterization of LDLr Variants
por: Benito-Vicente, Asier, et al.
Publicado: (2018)

Berberine decreases plasma triglyceride levels and upregulates hepatic TRIB1 in LDLR wild type mice and in LDLR deficient mice
por: Singh, Amar Bahadur, et al.
Publicado: (2019)

Postnatal Overfeeding Causes Early Shifts in Gene Expression in the Heart and Long-Term Alterations in Cardiometabolic and Oxidative Parameters
por: Habbout, Ahmed, et al.
Publicado: (2013)

Vitamin D(3) supplementation of a high fat high sugar diet ameliorates prediabetic phenotype in female LDLR(−/−) and LDLR(+/+) mice
por: Kheder, Ramiar, et al.
Publicado: (2017)

Molecular modeling of LDLR aids interpretation of genomic variants
por: Klee, Eric W., et al.
Publicado: (2019)

HVC1 ameliorates hyperlipidemia and inflammation in LDLR(−/−) mice
por: Cheon, Se-Yun, et al.
Publicado: (2017)

High-Throughput Microscopy Characterization of Rare LDLR Variants
por: Graça, Rafael, et al.
Publicado: (2023)

Large-Scale CRISPR Screen of LDLR Pathogenic Variants
por: Li, Mengjing, et al.
Publicado: (2023)

Evaluating the impact of varying expired carbon monoxide thresholds on smoking relapse identification: insights from the E3 trial on e-cigarette efficacy for smoking cessation
por: Prell, Celine, et al.
Publicado: (2023)

Time-Related Alteration in Flow- (Shear Stress-) Mediated Remodeling in Resistance Arteries from Spontaneously Hypertensive Rats
por: Dumont, Odile, et al.
Publicado: (2014)

Metabolic Signature of Remote Ischemic Preconditioning Involving a Cocktail of Amino Acids and Biogenic Amines
por: Chao de la Barca, Juan Manuel, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_pgpc3k513dav5q09qo69argodp