Generalized Approach towards Secretion-Based Protein Production via Neutralization of Secretion-Preventing Cationic Substrate Residues

Many heterologous proteins can be secreted by bacterial ATP-binding cassette (ABC) transporters, provided that they are fused with the C-terminal signal sequence, but some proteins are not secretable even though they carry the right signal sequence. The invention of a method to secrete these non-sec...

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Detalles Bibliográficos
Autores principales: Byun, Hyunjong, Park, Jiyeon, Fabia, Benedict U., Bingwa, Joshua, Nguyen, Mihn Hieu, Lee, Haeshin, Ahn, Jung Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223453/
https://www.ncbi.nlm.nih.gov/pubmed/35743142
http://dx.doi.org/10.3390/ijms23126700

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