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The Impact of Charlson Comorbidity Index on the Functional Capacity of COVID-19 Survivors: A Prospective Cohort Study with One-Year Follow-Up

Objective: To determine the association between the Charlson comorbidity index (CCI) score after discharge with 6-min walk test (6MWT) 1 year after discharge in a cohort of COVID-19 survivors. Methods: In this prospective study, data were collected from a consecutive sample of patients hospitalized...

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Autores principales: Núñez-Cortés, Rodrigo, Malhue-Vidal, Constanza, Gath, Florencia, Valdivia-Lobos, Gonzalo, Torres-Castro, Rodrigo, Cruz-Montecinos, Carlos, Martinez-Arnau, Francisco M., Pérez-Alenda, Sofía, López-Bueno, Rubén, Calatayud, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223623/
https://www.ncbi.nlm.nih.gov/pubmed/35742722
http://dx.doi.org/10.3390/ijerph19127473
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author Núñez-Cortés, Rodrigo
Malhue-Vidal, Constanza
Gath, Florencia
Valdivia-Lobos, Gonzalo
Torres-Castro, Rodrigo
Cruz-Montecinos, Carlos
Martinez-Arnau, Francisco M.
Pérez-Alenda, Sofía
López-Bueno, Rubén
Calatayud, Joaquín
author_facet Núñez-Cortés, Rodrigo
Malhue-Vidal, Constanza
Gath, Florencia
Valdivia-Lobos, Gonzalo
Torres-Castro, Rodrigo
Cruz-Montecinos, Carlos
Martinez-Arnau, Francisco M.
Pérez-Alenda, Sofía
López-Bueno, Rubén
Calatayud, Joaquín
author_sort Núñez-Cortés, Rodrigo
collection PubMed
description Objective: To determine the association between the Charlson comorbidity index (CCI) score after discharge with 6-min walk test (6MWT) 1 year after discharge in a cohort of COVID-19 survivors. Methods: In this prospective study, data were collected from a consecutive sample of patients hospitalized for COVID-19. The CCI score was calculated from the comorbidity data. The main outcome was the distance walked in the 6MWT at 1 year after discharge. Associations between CCI and meters covered in the 6MWT were assessed through crude and adjusted linear regressions. The model was adjusted for possible confounding factors (sex, days of hospitalization, and basal physical capacity through sit-to-stand test one month after discharge). Results: A total of 41 patients were included (mean age 58.8 ± 12.7 years, 20/21 men/women). A significant association was observed between CCI and 6MWT (meters): (i) crude model: β = −18.7, 95% CI = −34.7 to −2.6, p < 0.05; (ii) model adjusted for propensity score including sex, days of hospitalization, and sit-to-stand: β = −23.0, 95% CI = −39.1 to −6.8, p < 0.05. Conclusions: A higher CCI score after discharge indicates worse performance on the 6MWT at 1-year follow-up in COVID-19 survivors. The CCI score could also be used as a screening tool to make important clinical decisions.
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spelling pubmed-92236232022-06-24 The Impact of Charlson Comorbidity Index on the Functional Capacity of COVID-19 Survivors: A Prospective Cohort Study with One-Year Follow-Up Núñez-Cortés, Rodrigo Malhue-Vidal, Constanza Gath, Florencia Valdivia-Lobos, Gonzalo Torres-Castro, Rodrigo Cruz-Montecinos, Carlos Martinez-Arnau, Francisco M. Pérez-Alenda, Sofía López-Bueno, Rubén Calatayud, Joaquín Int J Environ Res Public Health Article Objective: To determine the association between the Charlson comorbidity index (CCI) score after discharge with 6-min walk test (6MWT) 1 year after discharge in a cohort of COVID-19 survivors. Methods: In this prospective study, data were collected from a consecutive sample of patients hospitalized for COVID-19. The CCI score was calculated from the comorbidity data. The main outcome was the distance walked in the 6MWT at 1 year after discharge. Associations between CCI and meters covered in the 6MWT were assessed through crude and adjusted linear regressions. The model was adjusted for possible confounding factors (sex, days of hospitalization, and basal physical capacity through sit-to-stand test one month after discharge). Results: A total of 41 patients were included (mean age 58.8 ± 12.7 years, 20/21 men/women). A significant association was observed between CCI and 6MWT (meters): (i) crude model: β = −18.7, 95% CI = −34.7 to −2.6, p < 0.05; (ii) model adjusted for propensity score including sex, days of hospitalization, and sit-to-stand: β = −23.0, 95% CI = −39.1 to −6.8, p < 0.05. Conclusions: A higher CCI score after discharge indicates worse performance on the 6MWT at 1-year follow-up in COVID-19 survivors. The CCI score could also be used as a screening tool to make important clinical decisions. MDPI 2022-06-18 /pmc/articles/PMC9223623/ /pubmed/35742722 http://dx.doi.org/10.3390/ijerph19127473 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Núñez-Cortés, Rodrigo
Malhue-Vidal, Constanza
Gath, Florencia
Valdivia-Lobos, Gonzalo
Torres-Castro, Rodrigo
Cruz-Montecinos, Carlos
Martinez-Arnau, Francisco M.
Pérez-Alenda, Sofía
López-Bueno, Rubén
Calatayud, Joaquín
The Impact of Charlson Comorbidity Index on the Functional Capacity of COVID-19 Survivors: A Prospective Cohort Study with One-Year Follow-Up
title The Impact of Charlson Comorbidity Index on the Functional Capacity of COVID-19 Survivors: A Prospective Cohort Study with One-Year Follow-Up
title_full The Impact of Charlson Comorbidity Index on the Functional Capacity of COVID-19 Survivors: A Prospective Cohort Study with One-Year Follow-Up
title_fullStr The Impact of Charlson Comorbidity Index on the Functional Capacity of COVID-19 Survivors: A Prospective Cohort Study with One-Year Follow-Up
title_full_unstemmed The Impact of Charlson Comorbidity Index on the Functional Capacity of COVID-19 Survivors: A Prospective Cohort Study with One-Year Follow-Up
title_short The Impact of Charlson Comorbidity Index on the Functional Capacity of COVID-19 Survivors: A Prospective Cohort Study with One-Year Follow-Up
title_sort impact of charlson comorbidity index on the functional capacity of covid-19 survivors: a prospective cohort study with one-year follow-up
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223623/
https://www.ncbi.nlm.nih.gov/pubmed/35742722
http://dx.doi.org/10.3390/ijerph19127473
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