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Combining Recombinase-Mediated Cassette Exchange Strategy with Quantitative Proteomic and Phosphoproteomic Analyses to Inspect Intracellular Functions of the Tumor Suppressor Galectin-4 in Colorectal Cancer Cells

Galectin-4 (Gal4) has been suggested to function as a tumor suppressor in colorectal cancer (CRC). In order to systematically explore its function in CRC, we established a CRC cell line where Gal4 expression can be regulated via the doxycycline (dox)-inducible expression of a single copy wildtype LG...

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Detalles Bibliográficos
Autores principales: Michalak, Malwina, Golde, Viola, Helm, Dominik, Kaltner, Herbert, Gebert, Johannes, Kopitz, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223697/
https://www.ncbi.nlm.nih.gov/pubmed/35742860
http://dx.doi.org/10.3390/ijms23126414