Bacterial Nucleotidyl Cyclases Activated by Calmodulin or Actin in Host Cells: Enzyme Specificities and Cytotoxicity Mechanisms Identified to Date

Many pathogens manipulate host cell cAMP signaling pathways to promote their survival and proliferation. Bacterial Exoenzyme Y (ExoY) toxins belong to a family of invasive, structurally-related bacterial nucleotidyl cyclases (NC). Inactive in bacteria, they use proteins that are uniquely and abundan...

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Detalles Bibliográficos
Autores principales: Teixeira-Nunes, Magda, Retailleau, Pascal, Comisso, Martine, Deruelle, Vincent, Mechold, Undine, Renault, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223806/
https://www.ncbi.nlm.nih.gov/pubmed/35743184
http://dx.doi.org/10.3390/ijms23126743

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