Proteolysis Targeting Chimeric Molecules: Tuning Molecular Strategies for a Clinically Sound Listening

From seminal evidence in the early 2000s, the opportunity to drive the specific knockdown of a protein of interest (POI) through pharmacological entities called Proteolysis Targeting Chimeric molecules, or PROTACs, has become a possible therapeutic option with the involvement of these compounds in c...

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Detalles Bibliográficos
Autores principales: Pedrucci, Federica, Pappalardo, Claudia, Marzaro, Giovanni, Ferri, Nicola, Ferlin, Alberto, De Toni, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223854/
https://www.ncbi.nlm.nih.gov/pubmed/35743070
http://dx.doi.org/10.3390/ijms23126630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223854/
https://www.ncbi.nlm.nih.gov/pubmed/35743070
http://dx.doi.org/10.3390/ijms23126630

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