Cargando…
Proteolysis Targeting Chimeric Molecules: Tuning Molecular Strategies for a Clinically Sound Listening
From seminal evidence in the early 2000s, the opportunity to drive the specific knockdown of a protein of interest (POI) through pharmacological entities called Proteolysis Targeting Chimeric molecules, or PROTACs, has become a possible therapeutic option with the involvement of these compounds in c...
Autores principales: | Pedrucci, Federica, Pappalardo, Claudia, Marzaro, Giovanni, Ferri, Nicola, Ferlin, Alberto, De Toni, Luca |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9223854/ https://www.ncbi.nlm.nih.gov/pubmed/35743070 http://dx.doi.org/10.3390/ijms23126630 |
Ejemplares similares
-
Ketone Body β-Hydroxy-Butyrate Sustains Progressive Motility in Capacitated Human Spermatozoa: A Possible Role in Natural Fertility
por: Pappalardo, Claudia, et al.
Publicado: (2023) -
Legacy perfluoro-alkyl substances impair LDL-cholesterol uptake independently from PCSK9-function
por: Sabovic, Iva, et al.
Publicado: (2023) -
Onomatopoeia – listening to the sounds behind the words
por: Schlegel, Claudia, et al.
Publicado: (2021) -
Proteolysis targeting chimeric molecules as therapy for multiple myeloma: efficacy, biomarker and drug combinations
por: Lim, Su Lin, et al.
Publicado: (2019) -
Multiple myeloma: Combination therapy of BET proteolysis targeting chimeric molecule with CDK9 inhibitor
por: Lim, Su-Lin, et al.
Publicado: (2020)