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Antioxidative Defense and Gut Microbial Changes under Pollution Stress in Carassius gibelio from Bucharest Lakes

Fish are able to accumulate by ingestion various contaminants of aquatic environment, with negative consequences on their intestine, being continuously threatened worldwide by heavy metals, pesticides and antibiotics resulted from the human activities. Consequently, the health of other species can b...

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Autores principales: Alistar, Cristina F., Nica, Ionela C., Nita-Lazar, Mihai, Vasile, Gabriela Geanina, Gheorghe, Stefania, Croitoru, Alexa-Maria, Dolete, Georgiana, Mihaiescu, Dan Eduard, Ficai, Anton, Craciun, Nicolai, Gradisteanu Pircalabioru, Gratiela, Chifiriuc, Mariana Carmen, Stan, Miruna S., Dinischiotu, Anca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224152/
https://www.ncbi.nlm.nih.gov/pubmed/35742758
http://dx.doi.org/10.3390/ijerph19127510
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author Alistar, Cristina F.
Nica, Ionela C.
Nita-Lazar, Mihai
Vasile, Gabriela Geanina
Gheorghe, Stefania
Croitoru, Alexa-Maria
Dolete, Georgiana
Mihaiescu, Dan Eduard
Ficai, Anton
Craciun, Nicolai
Gradisteanu Pircalabioru, Gratiela
Chifiriuc, Mariana Carmen
Stan, Miruna S.
Dinischiotu, Anca
author_facet Alistar, Cristina F.
Nica, Ionela C.
Nita-Lazar, Mihai
Vasile, Gabriela Geanina
Gheorghe, Stefania
Croitoru, Alexa-Maria
Dolete, Georgiana
Mihaiescu, Dan Eduard
Ficai, Anton
Craciun, Nicolai
Gradisteanu Pircalabioru, Gratiela
Chifiriuc, Mariana Carmen
Stan, Miruna S.
Dinischiotu, Anca
author_sort Alistar, Cristina F.
collection PubMed
description Fish are able to accumulate by ingestion various contaminants of aquatic environment, with negative consequences on their intestine, being continuously threatened worldwide by heavy metals, pesticides and antibiotics resulted from the human activities. Consequently, the health of other species can be affected by eating the contaminated fish meat. In this context, our study aimed to perform a comparison between the changes in intestine samples of Carassius gibelio individuals collected from different artificial lakes in Bucharest (Romania), used by people for leisure and fishing. The presence of various metals, pesticides and antibiotics in the gut of fish was assessed in order to correlate their accumulation with changes of antioxidative enzymes activities and microbiome. Our results showed that fish from Bucharest lakes designed for leisure (Chitila, Floreasca and Tei lakes) have an increased level of oxidative stress in intestine tissue, revealed by affected antioxidant enzymes activities and GSH levels, as well as the high degree of lipid peroxidation, compared to the fish from protected environment (Vacaresti Lake). Some heavy metals (Fe, Ni and Pb) and pesticides (aldrin and dieldrin) were in high amount in the gut of fish with modified antioxidative status. In conclusion, our study could improve the knowledge regarding the current state of urban aquatic pollution in order to impose several environmental health measures.
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spelling pubmed-92241522022-06-24 Antioxidative Defense and Gut Microbial Changes under Pollution Stress in Carassius gibelio from Bucharest Lakes Alistar, Cristina F. Nica, Ionela C. Nita-Lazar, Mihai Vasile, Gabriela Geanina Gheorghe, Stefania Croitoru, Alexa-Maria Dolete, Georgiana Mihaiescu, Dan Eduard Ficai, Anton Craciun, Nicolai Gradisteanu Pircalabioru, Gratiela Chifiriuc, Mariana Carmen Stan, Miruna S. Dinischiotu, Anca Int J Environ Res Public Health Article Fish are able to accumulate by ingestion various contaminants of aquatic environment, with negative consequences on their intestine, being continuously threatened worldwide by heavy metals, pesticides and antibiotics resulted from the human activities. Consequently, the health of other species can be affected by eating the contaminated fish meat. In this context, our study aimed to perform a comparison between the changes in intestine samples of Carassius gibelio individuals collected from different artificial lakes in Bucharest (Romania), used by people for leisure and fishing. The presence of various metals, pesticides and antibiotics in the gut of fish was assessed in order to correlate their accumulation with changes of antioxidative enzymes activities and microbiome. Our results showed that fish from Bucharest lakes designed for leisure (Chitila, Floreasca and Tei lakes) have an increased level of oxidative stress in intestine tissue, revealed by affected antioxidant enzymes activities and GSH levels, as well as the high degree of lipid peroxidation, compared to the fish from protected environment (Vacaresti Lake). Some heavy metals (Fe, Ni and Pb) and pesticides (aldrin and dieldrin) were in high amount in the gut of fish with modified antioxidative status. In conclusion, our study could improve the knowledge regarding the current state of urban aquatic pollution in order to impose several environmental health measures. MDPI 2022-06-19 /pmc/articles/PMC9224152/ /pubmed/35742758 http://dx.doi.org/10.3390/ijerph19127510 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Alistar, Cristina F.
Nica, Ionela C.
Nita-Lazar, Mihai
Vasile, Gabriela Geanina
Gheorghe, Stefania
Croitoru, Alexa-Maria
Dolete, Georgiana
Mihaiescu, Dan Eduard
Ficai, Anton
Craciun, Nicolai
Gradisteanu Pircalabioru, Gratiela
Chifiriuc, Mariana Carmen
Stan, Miruna S.
Dinischiotu, Anca
Antioxidative Defense and Gut Microbial Changes under Pollution Stress in Carassius gibelio from Bucharest Lakes
title Antioxidative Defense and Gut Microbial Changes under Pollution Stress in Carassius gibelio from Bucharest Lakes
title_full Antioxidative Defense and Gut Microbial Changes under Pollution Stress in Carassius gibelio from Bucharest Lakes
title_fullStr Antioxidative Defense and Gut Microbial Changes under Pollution Stress in Carassius gibelio from Bucharest Lakes
title_full_unstemmed Antioxidative Defense and Gut Microbial Changes under Pollution Stress in Carassius gibelio from Bucharest Lakes
title_short Antioxidative Defense and Gut Microbial Changes under Pollution Stress in Carassius gibelio from Bucharest Lakes
title_sort antioxidative defense and gut microbial changes under pollution stress in carassius gibelio from bucharest lakes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224152/
https://www.ncbi.nlm.nih.gov/pubmed/35742758
http://dx.doi.org/10.3390/ijerph19127510
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