HOXA9 Overexpression Contributes to Stem Cell Overpopulation That Drives Development and Growth of Colorectal Cancer

HOX proteins are transcription factors that regulate stem cell (SC) function, but their role in the SC origin of cancer is under-studied. Aberrant expression of HOX genes occurs in many cancer types. Our goal is to ascertain how retinoic acid (RA) signaling and the regulation of HOXA9 expression mig...

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Detalles Bibliográficos
Autores principales: Osmond, Brian, Facey, Caroline O. B., Zhang, Chi, Boman, Bruce M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224160/
https://www.ncbi.nlm.nih.gov/pubmed/35743243
http://dx.doi.org/10.3390/ijms23126799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224160/
https://www.ncbi.nlm.nih.gov/pubmed/35743243
http://dx.doi.org/10.3390/ijms23126799

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