Use of PET Imaging to Assess the Efficacy of Thiethylperazine to Stimulate Cerebral MRP1 Transport Activity in Wild-Type and APP/PS1-21 Mice

Multidrug resistance-associated protein 1 (MRP1, encoded by the ABCC1 gene) may contribute to the clearance of amyloid-beta (Aβ) peptides from the brain into the blood and stimulation of MRP1 transport activity may be a therapeutic approach to enhance brain Aβ clearance. In this study, we assessed t...

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Detalles Bibliográficos
Autores principales: Wölfl-Duchek, Michael, Mairinger, Severin, Hernández-Lozano, Irene, Filip, Thomas, Zoufal, Viktoria, Löbsch, Mathilde, Stanek, Johann, Kuntner, Claudia, Wanek, Thomas, Bauer, Martin, Pahnke, Jens, Langer, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224167/
https://www.ncbi.nlm.nih.gov/pubmed/35742960
http://dx.doi.org/10.3390/ijms23126514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224167/
https://www.ncbi.nlm.nih.gov/pubmed/35742960
http://dx.doi.org/10.3390/ijms23126514

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