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Thalamocortical Projections Are Significantly Impaired in the R6/2 Mouse Model of Huntington’s Disease

As Huntington’s disease (HD) progresses, there is a significant loss of neurons in the striatum in addition to a distinct thinning of the cerebral cortex. Despite an early presence of sensorimotor deficits in patients with HD, electrophysiological studies designed to assess the integrity of thalamoc...

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Detalles Bibliográficos
Autores principales: Holley, S. M., Oikonomou, K. D., Swift, C. M., Mohan, L., Matthews, B., Vega, O., Mkrtchyan, G., Cepeda, C., Levine, M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224171/
https://www.ncbi.nlm.nih.gov/pubmed/35667848
http://dx.doi.org/10.1523/ENEURO.0103-22.2022

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