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Thalamocortical Projections Are Significantly Impaired in the R6/2 Mouse Model of Huntington’s Disease
As Huntington’s disease (HD) progresses, there is a significant loss of neurons in the striatum in addition to a distinct thinning of the cerebral cortex. Despite an early presence of sensorimotor deficits in patients with HD, electrophysiological studies designed to assess the integrity of thalamoc...
Autores principales: | Holley, S. M., Oikonomou, K. D., Swift, C. M., Mohan, L., Matthews, B., Vega, O., Mkrtchyan, G., Cepeda, C., Levine, M. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224171/ https://www.ncbi.nlm.nih.gov/pubmed/35667848 http://dx.doi.org/10.1523/ENEURO.0103-22.2022 |
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