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Effects of Chronic LY341495 on Hippocampal mTORC1 Signaling in Mice with Chronic Unpredictable Stress-Induced Depression

In several rodent models, acute administration of the metabotropic glutamate 2/3 (mGlu2/3) receptor antagonist LY341495 induced antidepressant-like effects via a mechanism of action similar to that of ketamine. However, the effects of chronic mGlu2/3 antagonism have not yet been explored. Therefore,...

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Detalles Bibliográficos
Autores principales:	Seo, Mi Kyoung, Lee, Jung An, Jeong, Sehoon, Seog, Dae-Hyun, Lee, Jung Goo, Park, Sung Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224204/ https://www.ncbi.nlm.nih.gov/pubmed/35742857 http://dx.doi.org/10.3390/ijms23126416

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