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Combined Approach to Leukemic Differentiation Using Transcription Factor PU.1-Enhancing Agents

The transcription factor PU.1 (Purine-rich DNA binding, SPI1) is a key regulator of hematopoiesis, whose level is influenced by transcription through its enhancers and its post-transcriptional degradation via microRNA-155 (miR-155). The degree of transcriptional regulation of the PU.1 gene is influe...

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Detalles Bibliográficos
Autores principales: Bašová, Petra, Paszeková, Helena, Minařík, Lubomír, Dluhošová, Martina, Burda, Pavel, Stopka, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224232/
https://www.ncbi.nlm.nih.gov/pubmed/35743167
http://dx.doi.org/10.3390/ijms23126729