Generation and Characterization of a Tumor Stromal Microenvironment and Analysis of Its Interplay with Breast Cancer Cells: An In Vitro Model to Study Breast Cancer-Associated Fibroblast Inactivation

Breast cancer-associated fibroblasts (BCAFs), the most abundant non-cancer stromal cells of the breast tumor microenvironment (TME), dramatically sustain breast cancer (BC) progression by interacting with BC cells. BCAFs, as well as myofibroblasts, display an up regulation of activation and inflamma...

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Detalles Bibliográficos
Autores principales: Romano, Veronica, Ruocco, Maria Rosaria, Carotenuto, Pietro, Barbato, Anna, Venuta, Alessandro, Acampora, Vittoria, De Lella, Sabrina, Vigliar, Elena, Iaccarino, Antonino, Troncone, Giancarlo, Calì, Gaetano, Insabato, Luigi, Russo, Daniela, Franco, Brunella, Masone, Stefania, Velotti, Nunzio, Accurso, Antonello, Pellegrino, Tommaso, Fiume, Giuseppe, Belviso, Immacolata, Montagnani, Stefania, Avagliano, Angelica, Arcucci, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224278/
https://www.ncbi.nlm.nih.gov/pubmed/35743318
http://dx.doi.org/10.3390/ijms23126875

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