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Hypomethylation of CLDN4 Gene Promoter Is Associated with Malignant Phenotype in Urinary Bladder Cancer

The tight junction (TJ) protein claudin-4 (CLDN4) is overexpressed in bladder urothelial carcinoma (BUC) and correlates with cancer progression. However, the mechanism of CLDN4 upregulation and promotion of malignant phenotype is not clear. Here, we analyzed 157 cases of BUC and investigated the hyp...

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Detalles Bibliográficos
Autores principales:	Maesaka, Fumisato, Kuwada, Masaomi, Horii, Shohei, Kishi, Shingo, Fujiwara-Tani, Rina, Mori, Shiori, Fujii, Kiyomu, Mori, Takuya, Ohmori, Hitoshi, Owari, Takuya, Miyake, Makito, Nakai, Yasushi, Tanaka, Nobumichi, Bhawal, Ujjal Kumar, Luo, Yi, Kondoh, Masuo, Fujimoto, Kiyohide, Kuniyasu, Hiroki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224287/ https://www.ncbi.nlm.nih.gov/pubmed/35742959 http://dx.doi.org/10.3390/ijms23126516

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