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Profiling the Effect of Targeting Wild Isocitrate Dehydrogenase 1 (IDH1) on the Cellular Metabolome of Leukemic Cells

Leukemia is one of the most common primary malignancies of the hematologic system in both children and adults and remains a largely incurable or relapsing disease. The elucidation of disease subtypes based on mutational profiling has not improved clinical outcomes. IDH1/2 are critical enzymes of the...

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Detalles Bibliográficos
Autores principales:	Shait Mohammed, Mohammed Razeeth, Alzahrani, Faisal, Hosawi, Salman, Choudhry, Hani, Khan, Mohammad Imran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224363/ https://www.ncbi.nlm.nih.gov/pubmed/35743098 http://dx.doi.org/10.3390/ijms23126653

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