Monte Carlo Models for Sub-Chronic Repeated-Dose Toxicity: Systemic and Organ-Specific Toxicity

The risk-characterization of chemicals requires the determination of repeated-dose toxicity (RDT). This depends on two main outcomes: the no-observed-adverse-effect level (NOAEL) and the lowest-observed-adverse-effect level (LOAEL). These endpoints are fundamental requirements in several regulatory...

Descripción completa

Detalles Bibliográficos
Autores principales: Selvestrel, Gianluca, Lavado, Giovanna J., Toropova, Alla P., Toropov, Andrey A., Gadaleta, Domenico, Marzo, Marco, Baderna, Diego, Benfenati, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224506/
https://www.ncbi.nlm.nih.gov/pubmed/35743059
http://dx.doi.org/10.3390/ijms23126615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224506/
https://www.ncbi.nlm.nih.gov/pubmed/35743059
http://dx.doi.org/10.3390/ijms23126615

Ejemplares similares