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Monte Carlo Models for Sub-Chronic Repeated-Dose Toxicity: Systemic and Organ-Specific Toxicity

The risk-characterization of chemicals requires the determination of repeated-dose toxicity (RDT). This depends on two main outcomes: the no-observed-adverse-effect level (NOAEL) and the lowest-observed-adverse-effect level (LOAEL). These endpoints are fundamental requirements in several regulatory...

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Detalles Bibliográficos
Autores principales:	Selvestrel, Gianluca, Lavado, Giovanna J., Toropova, Alla P., Toropov, Andrey A., Gadaleta, Domenico, Marzo, Marco, Baderna, Diego, Benfenati, Emilio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224506/ https://www.ncbi.nlm.nih.gov/pubmed/35743059 http://dx.doi.org/10.3390/ijms23126615

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