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Calcification in Salivary Gland Cancer Mimicking Sialolithiasis—A Diagnostic Pitfall on Imaging: Report of Two Cases and Brief Review of the Literature

Objectives: Sialolithiasis is the most common cause of calcifications detected with ultrasound in patients with chronic inflammatory symptoms and swellings of the salivary glands. Other differential diagnoses of calcifications are extremely rare and mostly benign. Methods: Case report and literature...

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Autores principales: Thimsen, Vivian, Fauck, Vanessa, Wiesmüller, Marco, Agaimy, Abbas, Schapher, Mirco, Iro, Heinrich, Koch, Michael, Mantsopoulos, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224696/
https://www.ncbi.nlm.nih.gov/pubmed/35743400
http://dx.doi.org/10.3390/jcm11123329
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author Thimsen, Vivian
Fauck, Vanessa
Wiesmüller, Marco
Agaimy, Abbas
Schapher, Mirco
Iro, Heinrich
Koch, Michael
Mantsopoulos, Konstantinos
author_facet Thimsen, Vivian
Fauck, Vanessa
Wiesmüller, Marco
Agaimy, Abbas
Schapher, Mirco
Iro, Heinrich
Koch, Michael
Mantsopoulos, Konstantinos
author_sort Thimsen, Vivian
collection PubMed
description Objectives: Sialolithiasis is the most common cause of calcifications detected with ultrasound in patients with chronic inflammatory symptoms and swellings of the salivary glands. Other differential diagnoses of calcifications are extremely rare and mostly benign. Methods: Case report and literature review. Results: Two rare cases of malignant parotid gland tumors with calcifications in a localization typical for sialolithiasis, which were mistaken for salivary calculi based on image findings, are presented. Conclusions: This report intends to highlight the pitfalls in the imaging of parotid gland diseases. Even if malignant tumors of the parotid gland with calcifications are extremely rare, in ambiguous cases, differential diagnoses should be considered carefully. A high suspicion index of the need for further diagnostics in cases with calcifications is practical and could include missing periprandial symptoms, no obstruction signs in the proximal duct, and missing evidence of sialolithiasis in sialendoscopy.
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spelling pubmed-92246962022-06-24 Calcification in Salivary Gland Cancer Mimicking Sialolithiasis—A Diagnostic Pitfall on Imaging: Report of Two Cases and Brief Review of the Literature Thimsen, Vivian Fauck, Vanessa Wiesmüller, Marco Agaimy, Abbas Schapher, Mirco Iro, Heinrich Koch, Michael Mantsopoulos, Konstantinos J Clin Med Case Report Objectives: Sialolithiasis is the most common cause of calcifications detected with ultrasound in patients with chronic inflammatory symptoms and swellings of the salivary glands. Other differential diagnoses of calcifications are extremely rare and mostly benign. Methods: Case report and literature review. Results: Two rare cases of malignant parotid gland tumors with calcifications in a localization typical for sialolithiasis, which were mistaken for salivary calculi based on image findings, are presented. Conclusions: This report intends to highlight the pitfalls in the imaging of parotid gland diseases. Even if malignant tumors of the parotid gland with calcifications are extremely rare, in ambiguous cases, differential diagnoses should be considered carefully. A high suspicion index of the need for further diagnostics in cases with calcifications is practical and could include missing periprandial symptoms, no obstruction signs in the proximal duct, and missing evidence of sialolithiasis in sialendoscopy. MDPI 2022-06-10 /pmc/articles/PMC9224696/ /pubmed/35743400 http://dx.doi.org/10.3390/jcm11123329 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Thimsen, Vivian
Fauck, Vanessa
Wiesmüller, Marco
Agaimy, Abbas
Schapher, Mirco
Iro, Heinrich
Koch, Michael
Mantsopoulos, Konstantinos
Calcification in Salivary Gland Cancer Mimicking Sialolithiasis—A Diagnostic Pitfall on Imaging: Report of Two Cases and Brief Review of the Literature
title Calcification in Salivary Gland Cancer Mimicking Sialolithiasis—A Diagnostic Pitfall on Imaging: Report of Two Cases and Brief Review of the Literature
title_full Calcification in Salivary Gland Cancer Mimicking Sialolithiasis—A Diagnostic Pitfall on Imaging: Report of Two Cases and Brief Review of the Literature
title_fullStr Calcification in Salivary Gland Cancer Mimicking Sialolithiasis—A Diagnostic Pitfall on Imaging: Report of Two Cases and Brief Review of the Literature
title_full_unstemmed Calcification in Salivary Gland Cancer Mimicking Sialolithiasis—A Diagnostic Pitfall on Imaging: Report of Two Cases and Brief Review of the Literature
title_short Calcification in Salivary Gland Cancer Mimicking Sialolithiasis—A Diagnostic Pitfall on Imaging: Report of Two Cases and Brief Review of the Literature
title_sort calcification in salivary gland cancer mimicking sialolithiasis—a diagnostic pitfall on imaging: report of two cases and brief review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224696/
https://www.ncbi.nlm.nih.gov/pubmed/35743400
http://dx.doi.org/10.3390/jcm11123329
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