Genome-Wide Analyses of Nephrotoxicity in Platinum-Treated Cancer Patients Identify Association with Genetic Variant in RBMS3 and Acute Kidney Injury

Nephrotoxicity is a common and dose-limiting side effect of platinum compounds, which often manifests as acute kidney injury or hypomagnesemia. This study aimed to investigate the genetic risk loci for platinum-induced nephrotoxicity. Platinum-treated brain tumor and head–neck tumor patients were ge...

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Detalles Bibliográficos
Autores principales: Klumpers, Marije J., Witte, Ward De, Gattuso, Giovanna, Schiavello, Elisabetta, Terenziani, Monica, Massimino, Maura, Gidding, Corrie E. M., Vermeulen, Sita H., Driessen, Chantal M., van Herpen, Carla M., van Meerten, Esther, Guchelaar, Henk-Jan, Coenen, Marieke J. H., te Loo, D. Maroeska W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224783/
https://www.ncbi.nlm.nih.gov/pubmed/35743677
http://dx.doi.org/10.3390/jpm12060892

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