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Evaluation of a Proportional–Integral–Derivative Controller for Hemorrhage Resuscitation Using a Hardware-in-Loop Test Platform

Hemorrhage is a leading cause of preventable death in trauma, which can often be avoided with proper fluid resuscitation. Fluid administration can be cognitive-demanding for medical personnel as the rates and volumes must be personalized to the trauma due to variations in injury severity and overall...

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Autores principales: Snider, Eric J., Berard, David, Vega, Saul J., Avital, Guy, Boice, Emily N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224865/
https://www.ncbi.nlm.nih.gov/pubmed/35743762
http://dx.doi.org/10.3390/jpm12060979
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author Snider, Eric J.
Berard, David
Vega, Saul J.
Avital, Guy
Boice, Emily N.
author_facet Snider, Eric J.
Berard, David
Vega, Saul J.
Avital, Guy
Boice, Emily N.
author_sort Snider, Eric J.
collection PubMed
description Hemorrhage is a leading cause of preventable death in trauma, which can often be avoided with proper fluid resuscitation. Fluid administration can be cognitive-demanding for medical personnel as the rates and volumes must be personalized to the trauma due to variations in injury severity and overall fluid responsiveness. Thus, automated fluid administration systems are ideal to simplify hemorrhagic shock resuscitation if properly designed for a wide range of hemorrhage scenarios. Here, we highlight the development of a proportional–integral–derivative (PID) controller using a hardware-in-loop test platform. The controller relies only on an input data stream of arterial pressure and a target pressure; the PID controller then outputs infusion rates to stabilize the subject. To evaluate PID controller performance with more than 10 controller metrics, the hardware-in-loop platform allowed for 11 different trauma-relevant hemorrhage scenarios for the controller to resuscitate against. Overall, the two controller configurations performed uniquely for the scenarios, with one reaching the target quicker but often overshooting, while the other rarely overshot the target but failed to reach the target during severe hemorrhage. In conclusion, PID controllers have the potential to simplify hemorrhage resuscitation if properly designed and evaluated, which can be accomplished with the test platform shown here.
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spelling pubmed-92248652022-06-24 Evaluation of a Proportional–Integral–Derivative Controller for Hemorrhage Resuscitation Using a Hardware-in-Loop Test Platform Snider, Eric J. Berard, David Vega, Saul J. Avital, Guy Boice, Emily N. J Pers Med Article Hemorrhage is a leading cause of preventable death in trauma, which can often be avoided with proper fluid resuscitation. Fluid administration can be cognitive-demanding for medical personnel as the rates and volumes must be personalized to the trauma due to variations in injury severity and overall fluid responsiveness. Thus, automated fluid administration systems are ideal to simplify hemorrhagic shock resuscitation if properly designed for a wide range of hemorrhage scenarios. Here, we highlight the development of a proportional–integral–derivative (PID) controller using a hardware-in-loop test platform. The controller relies only on an input data stream of arterial pressure and a target pressure; the PID controller then outputs infusion rates to stabilize the subject. To evaluate PID controller performance with more than 10 controller metrics, the hardware-in-loop platform allowed for 11 different trauma-relevant hemorrhage scenarios for the controller to resuscitate against. Overall, the two controller configurations performed uniquely for the scenarios, with one reaching the target quicker but often overshooting, while the other rarely overshot the target but failed to reach the target during severe hemorrhage. In conclusion, PID controllers have the potential to simplify hemorrhage resuscitation if properly designed and evaluated, which can be accomplished with the test platform shown here. MDPI 2022-06-16 /pmc/articles/PMC9224865/ /pubmed/35743762 http://dx.doi.org/10.3390/jpm12060979 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Snider, Eric J.
Berard, David
Vega, Saul J.
Avital, Guy
Boice, Emily N.
Evaluation of a Proportional–Integral–Derivative Controller for Hemorrhage Resuscitation Using a Hardware-in-Loop Test Platform
title Evaluation of a Proportional–Integral–Derivative Controller for Hemorrhage Resuscitation Using a Hardware-in-Loop Test Platform
title_full Evaluation of a Proportional–Integral–Derivative Controller for Hemorrhage Resuscitation Using a Hardware-in-Loop Test Platform
title_fullStr Evaluation of a Proportional–Integral–Derivative Controller for Hemorrhage Resuscitation Using a Hardware-in-Loop Test Platform
title_full_unstemmed Evaluation of a Proportional–Integral–Derivative Controller for Hemorrhage Resuscitation Using a Hardware-in-Loop Test Platform
title_short Evaluation of a Proportional–Integral–Derivative Controller for Hemorrhage Resuscitation Using a Hardware-in-Loop Test Platform
title_sort evaluation of a proportional–integral–derivative controller for hemorrhage resuscitation using a hardware-in-loop test platform
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224865/
https://www.ncbi.nlm.nih.gov/pubmed/35743762
http://dx.doi.org/10.3390/jpm12060979
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