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Systematic Cardiovascular Screening in Olympic Athletes before and after SARS-CoV-2 Infection

Conflicting results on the cardiovascular involvement after SARS-CoV-2 infection generated concerns on the safety of return-to-play (RTP) in athletes. The aim of this study was to evaluate the prevalence of cardiac involvement after COVID-19 in Olympic athletes, who had previously been screened in o...

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Autores principales: Maestrini, Viviana, Filomena, Domenico, Birtolo, Lucia Ilaria, Serdoz, Andrea, Fiore, Roberto, Tatangelo, Mario, Lemme, Erika, Squeo, Maria Rosaria, Mango, Ruggiero, Di Gioia, Giuseppe, Fedele, Francesco, Gualdi, Gianfranco, Spataro, Antonio, Pelliccia, Antonio, Di Giacinto, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224878/
https://www.ncbi.nlm.nih.gov/pubmed/35743567
http://dx.doi.org/10.3390/jcm11123499
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author Maestrini, Viviana
Filomena, Domenico
Birtolo, Lucia Ilaria
Serdoz, Andrea
Fiore, Roberto
Tatangelo, Mario
Lemme, Erika
Squeo, Maria Rosaria
Mango, Ruggiero
Di Gioia, Giuseppe
Fedele, Francesco
Gualdi, Gianfranco
Spataro, Antonio
Pelliccia, Antonio
Di Giacinto, Barbara
author_facet Maestrini, Viviana
Filomena, Domenico
Birtolo, Lucia Ilaria
Serdoz, Andrea
Fiore, Roberto
Tatangelo, Mario
Lemme, Erika
Squeo, Maria Rosaria
Mango, Ruggiero
Di Gioia, Giuseppe
Fedele, Francesco
Gualdi, Gianfranco
Spataro, Antonio
Pelliccia, Antonio
Di Giacinto, Barbara
author_sort Maestrini, Viviana
collection PubMed
description Conflicting results on the cardiovascular involvement after SARS-CoV-2 infection generated concerns on the safety of return-to-play (RTP) in athletes. The aim of this study was to evaluate the prevalence of cardiac involvement after COVID-19 in Olympic athletes, who had previously been screened in our pre-participation program. Since November 2020, all consecutive Olympic athletes presented to our Institute after COVID-19 prior to RTP were enrolled. The protocol was dictated by the Italian governing bodies and comprised: 12-lead ECG, blood test, cardiopulmonary exercise test (CPET), 24-h ECG monitoring, and spirometry. Cardiovascular Magnetic Resonance (CMR) was also performed. All Athletes were previously screened in our Institute as part of their periodical pre-participation evaluation. Forty-seven Italian Olympic athletes were enrolled: 83% asymptomatic, 13% mildly asymptomatic, and 4% had pneumonia. Uncommon premature ventricular contractions (PVCs) were found in 13% athletes; however, only 6% (n = 3) were newly detected. All newly diagnosed uncommon PVCs were detected by CPET. One of these three athletes had evidence for acute myocarditis by CMR, along with Troponin raise; another had pericardial effusion. No one of the remaining athletes had abnormalities detected by CMR. Cardiac abnormalities in Olympic athletes screened after COVID-19 resolution were detected in a minority, and were associated with new ventricular arrhythmias. Only one had evidence for acute myocarditis (in the presence of symptoms and elevated biomarkers). Our data support the efficacy of the clinical assessment including exercise-ECG to raise suspicion for cardiovascular abnormalities after COVID-19. Instead, the routine use of CMR as a screening tool appears unjustified.
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spelling pubmed-92248782022-06-24 Systematic Cardiovascular Screening in Olympic Athletes before and after SARS-CoV-2 Infection Maestrini, Viviana Filomena, Domenico Birtolo, Lucia Ilaria Serdoz, Andrea Fiore, Roberto Tatangelo, Mario Lemme, Erika Squeo, Maria Rosaria Mango, Ruggiero Di Gioia, Giuseppe Fedele, Francesco Gualdi, Gianfranco Spataro, Antonio Pelliccia, Antonio Di Giacinto, Barbara J Clin Med Article Conflicting results on the cardiovascular involvement after SARS-CoV-2 infection generated concerns on the safety of return-to-play (RTP) in athletes. The aim of this study was to evaluate the prevalence of cardiac involvement after COVID-19 in Olympic athletes, who had previously been screened in our pre-participation program. Since November 2020, all consecutive Olympic athletes presented to our Institute after COVID-19 prior to RTP were enrolled. The protocol was dictated by the Italian governing bodies and comprised: 12-lead ECG, blood test, cardiopulmonary exercise test (CPET), 24-h ECG monitoring, and spirometry. Cardiovascular Magnetic Resonance (CMR) was also performed. All Athletes were previously screened in our Institute as part of their periodical pre-participation evaluation. Forty-seven Italian Olympic athletes were enrolled: 83% asymptomatic, 13% mildly asymptomatic, and 4% had pneumonia. Uncommon premature ventricular contractions (PVCs) were found in 13% athletes; however, only 6% (n = 3) were newly detected. All newly diagnosed uncommon PVCs were detected by CPET. One of these three athletes had evidence for acute myocarditis by CMR, along with Troponin raise; another had pericardial effusion. No one of the remaining athletes had abnormalities detected by CMR. Cardiac abnormalities in Olympic athletes screened after COVID-19 resolution were detected in a minority, and were associated with new ventricular arrhythmias. Only one had evidence for acute myocarditis (in the presence of symptoms and elevated biomarkers). Our data support the efficacy of the clinical assessment including exercise-ECG to raise suspicion for cardiovascular abnormalities after COVID-19. Instead, the routine use of CMR as a screening tool appears unjustified. MDPI 2022-06-17 /pmc/articles/PMC9224878/ /pubmed/35743567 http://dx.doi.org/10.3390/jcm11123499 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Maestrini, Viviana
Filomena, Domenico
Birtolo, Lucia Ilaria
Serdoz, Andrea
Fiore, Roberto
Tatangelo, Mario
Lemme, Erika
Squeo, Maria Rosaria
Mango, Ruggiero
Di Gioia, Giuseppe
Fedele, Francesco
Gualdi, Gianfranco
Spataro, Antonio
Pelliccia, Antonio
Di Giacinto, Barbara
Systematic Cardiovascular Screening in Olympic Athletes before and after SARS-CoV-2 Infection
title Systematic Cardiovascular Screening in Olympic Athletes before and after SARS-CoV-2 Infection
title_full Systematic Cardiovascular Screening in Olympic Athletes before and after SARS-CoV-2 Infection
title_fullStr Systematic Cardiovascular Screening in Olympic Athletes before and after SARS-CoV-2 Infection
title_full_unstemmed Systematic Cardiovascular Screening in Olympic Athletes before and after SARS-CoV-2 Infection
title_short Systematic Cardiovascular Screening in Olympic Athletes before and after SARS-CoV-2 Infection
title_sort systematic cardiovascular screening in olympic athletes before and after sars-cov-2 infection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224878/
https://www.ncbi.nlm.nih.gov/pubmed/35743567
http://dx.doi.org/10.3390/jcm11123499
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