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VH3-53/66-Class RBD-Specific Human Monoclonal Antibody iB20 Displays Cross-Neutralizing Activity against Emerging SARS-CoV-2 Lineages
Immune evasion of SARS-CoV-2 undermines current strategies tocounteract the pandemic, with the efficacy of therapeutic virus-neutralizing monoclonal antibodies (nAbs) being affected the most. In this work, we asked whether two previously identified human cross-neutralizing nAbs, iB14 (class VH1-58)...
Autores principales: | Kulemzin, Sergey V., Sergeeva, Maria V., Baranov, Konstantin O., Gorchakov, Andrey A., Guselnikov, Sergey V., Belovezhets, Tatyana N., Volkova, Olga Yu., Najakshin, Alexander M., Chikaev, Nikolai A., Danilenko, Daria M., Taranin, Alexander V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224930/ https://www.ncbi.nlm.nih.gov/pubmed/35743680 http://dx.doi.org/10.3390/jpm12060895 |
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