DOG1-Positive Primary Mesenteric Leiomyosarcoma: Report of a Case and Review of the Literature

The mesentery constitutes a common location for the metastatic spread of malignant gastrointestinal tumors. Primary mesenteric tumors, on the other hand, are very rare; lymphomas are the most common, followed by benign and malignant mesenchymal tumors. We present a case of a 43-year-old patient oper...

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Detalles Bibliográficos
Autores principales: Koufopoulos, Nektarios, Damaskou, Vasileia, Siozopoulou, Vasiliki, Kokoropoulos, Panagiotis, Gouloumis, Alina-Roxani, Arkadopoulos, Nikolaos, Panayiotides, Ioannis G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224980/
https://www.ncbi.nlm.nih.gov/pubmed/35755504
http://dx.doi.org/10.7759/cureus.25263
Descripción
Sumario:The mesentery constitutes a common location for the metastatic spread of malignant gastrointestinal tumors. Primary mesenteric tumors, on the other hand, are very rare; lymphomas are the most common, followed by benign and malignant mesenchymal tumors. We present a case of a 43-year-old patient operated on for a primary mesenteric leiomyosarcoma with a positive immunostain for DOG1, despite having no KIT or PDGFRa mutations on molecular analysis. Moreover, we review the pertinent literature. 

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