Metabolic basis for the evolution of a common pathogenic Pseudomonas aeruginosa variant

Microbes frequently evolve in reproducible ways. Here, we show that differences in specific metabolic regulation rather than inter-strain interactions explain the frequent presence of lasR loss-of-function (LOF) mutations in the bacterial pathogen Pseudomonas aeruginosa. While LasR contributes to vi...

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Detalles Bibliográficos
Autores principales: Mould, Dallas L, Stevanovic, Mirjana, Ashare, Alix, Schultz, Daniel, Hogan, Deborah A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224983/
https://www.ncbi.nlm.nih.gov/pubmed/35502894
http://dx.doi.org/10.7554/eLife.76555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224983/
https://www.ncbi.nlm.nih.gov/pubmed/35502894
http://dx.doi.org/10.7554/eLife.76555

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