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Metabolic basis for the evolution of a common pathogenic Pseudomonas aeruginosa variant
Microbes frequently evolve in reproducible ways. Here, we show that differences in specific metabolic regulation rather than inter-strain interactions explain the frequent presence of lasR loss-of-function (LOF) mutations in the bacterial pathogen Pseudomonas aeruginosa. While LasR contributes to vi...
Autores principales: | Mould, Dallas L, Stevanovic, Mirjana, Ashare, Alix, Schultz, Daniel, Hogan, Deborah A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224983/ https://www.ncbi.nlm.nih.gov/pubmed/35502894 http://dx.doi.org/10.7554/eLife.76555 |
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