Stereotactic Radiotherapy: An Alternative Option for Refractory Ventricular Tachycardia to Drug and Ablation Therapy

Refractory ventricular tachycardia (VT) often occurs in the context of organic heart disease. It is associated with significantly high mortality and morbidity rates. Antiarrhythmic drugs and catheter ablation represent the two main treatment options for refractory VT, but their use can be associated...

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Autores principales: Shangguan, Wenfeng, Xu, Gang, Wang, Xin, Zhang, Nan, Liu, Xingpeng, Li, Guangping, Tse, Gary, Liu, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225049/
https://www.ncbi.nlm.nih.gov/pubmed/35743614
http://dx.doi.org/10.3390/jcm11123549
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author Shangguan, Wenfeng
Xu, Gang
Wang, Xin
Zhang, Nan
Liu, Xingpeng
Li, Guangping
Tse, Gary
Liu, Tong
author_facet Shangguan, Wenfeng
Xu, Gang
Wang, Xin
Zhang, Nan
Liu, Xingpeng
Li, Guangping
Tse, Gary
Liu, Tong
author_sort Shangguan, Wenfeng
collection PubMed
description Refractory ventricular tachycardia (VT) often occurs in the context of organic heart disease. It is associated with significantly high mortality and morbidity rates. Antiarrhythmic drugs and catheter ablation represent the two main treatment options for refractory VT, but their use can be associated with inadequate therapeutic responses and procedure-related complications. Stereotactic body radiotherapy (SBRT) is extensively applied in the precision treatment of solid tumors, with excellent therapeutic responses. Recently, this highly precise technology has been applied for radioablation of VT, and its early results demonstrate a favorable safety profile. This review presents the potential value of SBRT in refractory VT.
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spelling pubmed-92250492022-06-24 Stereotactic Radiotherapy: An Alternative Option for Refractory Ventricular Tachycardia to Drug and Ablation Therapy Shangguan, Wenfeng Xu, Gang Wang, Xin Zhang, Nan Liu, Xingpeng Li, Guangping Tse, Gary Liu, Tong J Clin Med Review Refractory ventricular tachycardia (VT) often occurs in the context of organic heart disease. It is associated with significantly high mortality and morbidity rates. Antiarrhythmic drugs and catheter ablation represent the two main treatment options for refractory VT, but their use can be associated with inadequate therapeutic responses and procedure-related complications. Stereotactic body radiotherapy (SBRT) is extensively applied in the precision treatment of solid tumors, with excellent therapeutic responses. Recently, this highly precise technology has been applied for radioablation of VT, and its early results demonstrate a favorable safety profile. This review presents the potential value of SBRT in refractory VT. MDPI 2022-06-20 /pmc/articles/PMC9225049/ /pubmed/35743614 http://dx.doi.org/10.3390/jcm11123549 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Shangguan, Wenfeng
Xu, Gang
Wang, Xin
Zhang, Nan
Liu, Xingpeng
Li, Guangping
Tse, Gary
Liu, Tong
Stereotactic Radiotherapy: An Alternative Option for Refractory Ventricular Tachycardia to Drug and Ablation Therapy
title Stereotactic Radiotherapy: An Alternative Option for Refractory Ventricular Tachycardia to Drug and Ablation Therapy
title_full Stereotactic Radiotherapy: An Alternative Option for Refractory Ventricular Tachycardia to Drug and Ablation Therapy
title_fullStr Stereotactic Radiotherapy: An Alternative Option for Refractory Ventricular Tachycardia to Drug and Ablation Therapy
title_full_unstemmed Stereotactic Radiotherapy: An Alternative Option for Refractory Ventricular Tachycardia to Drug and Ablation Therapy
title_short Stereotactic Radiotherapy: An Alternative Option for Refractory Ventricular Tachycardia to Drug and Ablation Therapy
title_sort stereotactic radiotherapy: an alternative option for refractory ventricular tachycardia to drug and ablation therapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225049/
https://www.ncbi.nlm.nih.gov/pubmed/35743614
http://dx.doi.org/10.3390/jcm11123549
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