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Comment on Ceruti et al. Temporal Changes in the Oxyhemoglobin Dissociation Curve of Critically Ill COVID-19 Patients. J. Clin. Med. 2022, 11, 788

Ceruti et al. describe in their article very low standard half saturation pressures (P(50)) in COVID-19 patients, calculated with the Dash et al. equations. By using the Hill equation and Severinghaus‘ coefficients we obtained normal values. The authors who do not present a pathophysiological cause...

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Detalles Bibliográficos
Autores principales: Böning, Dieter, Bloch, Wilhelm, Kuebler, Wolfgang M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225162/
https://www.ncbi.nlm.nih.gov/pubmed/35743447
http://dx.doi.org/10.3390/jcm11123376
Descripción
Sumario:Ceruti et al. describe in their article very low standard half saturation pressures (P(50)) in COVID-19 patients, calculated with the Dash et al. equations. By using the Hill equation and Severinghaus‘ coefficients we obtained normal values. The authors who do not present a pathophysiological cause for their results should explain this discrepancy. Independent of the absolute values a continuous moderate decrease of P(50) in the surviving patients might be of clinical importance.