Comment on Ceruti et al. Temporal Changes in the Oxyhemoglobin Dissociation Curve of Critically Ill COVID-19 Patients. J. Clin. Med. 2022, 11, 788

Ceruti et al. describe in their article very low standard half saturation pressures (P(50)) in COVID-19 patients, calculated with the Dash et al. equations. By using the Hill equation and Severinghaus‘ coefficients we obtained normal values. The authors who do not present a pathophysiological cause...

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Detalles Bibliográficos
Autores principales: Böning, Dieter, Bloch, Wilhelm, Kuebler, Wolfgang M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225162/
https://www.ncbi.nlm.nih.gov/pubmed/35743447
http://dx.doi.org/10.3390/jcm11123376
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author Böning, Dieter
Bloch, Wilhelm
Kuebler, Wolfgang M.
author_facet Böning, Dieter
Bloch, Wilhelm
Kuebler, Wolfgang M.
author_sort Böning, Dieter
collection PubMed
description Ceruti et al. describe in their article very low standard half saturation pressures (P(50)) in COVID-19 patients, calculated with the Dash et al. equations. By using the Hill equation and Severinghaus‘ coefficients we obtained normal values. The authors who do not present a pathophysiological cause for their results should explain this discrepancy. Independent of the absolute values a continuous moderate decrease of P(50) in the surviving patients might be of clinical importance.
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spelling pubmed-92251622022-06-24 Comment on Ceruti et al. Temporal Changes in the Oxyhemoglobin Dissociation Curve of Critically Ill COVID-19 Patients. J. Clin. Med. 2022, 11, 788 Böning, Dieter Bloch, Wilhelm Kuebler, Wolfgang M. J Clin Med Comment Ceruti et al. describe in their article very low standard half saturation pressures (P(50)) in COVID-19 patients, calculated with the Dash et al. equations. By using the Hill equation and Severinghaus‘ coefficients we obtained normal values. The authors who do not present a pathophysiological cause for their results should explain this discrepancy. Independent of the absolute values a continuous moderate decrease of P(50) in the surviving patients might be of clinical importance. MDPI 2022-06-13 /pmc/articles/PMC9225162/ /pubmed/35743447 http://dx.doi.org/10.3390/jcm11123376 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Comment
Böning, Dieter
Bloch, Wilhelm
Kuebler, Wolfgang M.
Comment on Ceruti et al. Temporal Changes in the Oxyhemoglobin Dissociation Curve of Critically Ill COVID-19 Patients. J. Clin. Med. 2022, 11, 788
title Comment on Ceruti et al. Temporal Changes in the Oxyhemoglobin Dissociation Curve of Critically Ill COVID-19 Patients. J. Clin. Med. 2022, 11, 788
title_full Comment on Ceruti et al. Temporal Changes in the Oxyhemoglobin Dissociation Curve of Critically Ill COVID-19 Patients. J. Clin. Med. 2022, 11, 788
title_fullStr Comment on Ceruti et al. Temporal Changes in the Oxyhemoglobin Dissociation Curve of Critically Ill COVID-19 Patients. J. Clin. Med. 2022, 11, 788
title_full_unstemmed Comment on Ceruti et al. Temporal Changes in the Oxyhemoglobin Dissociation Curve of Critically Ill COVID-19 Patients. J. Clin. Med. 2022, 11, 788
title_short Comment on Ceruti et al. Temporal Changes in the Oxyhemoglobin Dissociation Curve of Critically Ill COVID-19 Patients. J. Clin. Med. 2022, 11, 788
title_sort comment on ceruti et al. temporal changes in the oxyhemoglobin dissociation curve of critically ill covid-19 patients. j. clin. med. 2022, 11, 788
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225162/
https://www.ncbi.nlm.nih.gov/pubmed/35743447
http://dx.doi.org/10.3390/jcm11123376
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