A phase I randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, and immunogenicity of a live-attenuated quadrivalent dengue vaccine in flavivirus-naïve and flavivirus-experienced healthy adults

Dengue (DENV) is a mosquito-borne virus with four serotypes causing substantial morbidity in tropical and subtropical areas worldwide. V181 is an investigational, live, attenuated, quadrivalent dengue vaccine. In this phase 1 double-blind, placebo-controlled study, the safety, tolerability, and immu...

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Detalles Bibliográficos
Autores principales: Russell, Kevin L., Rupp, Richard E., Morales-Ramirez, Javier O., Diaz-Perez, Clemente, Andrews, Charles P., Lee, Andrew W., Finn, Tyler S., Cox, Kara S., Falk Russell, Amy, Schaller, Margaret M., Martin, Jason C., Hyatt, Donna M., Gozlan-Kelner, Sabrina, Bili, Androniki, Coller, Beth-Ann G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Novel Vaccines – Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225326/
https://www.ncbi.nlm.nih.gov/pubmed/35290152
http://dx.doi.org/10.1080/21645515.2022.2046960

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