Cargando…

Recent Advances in the Heterologous Expression of Biosynthetic Gene Clusters for Marine Natural Products

Marine natural products (MNPs) are an important source of biologically active metabolites, particularly for therapeutic agent development after terrestrial plants and nonmarine microorganisms. Sequencing technologies have revealed that the number of biosynthetic gene clusters (BGCs) in marine microo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Yushan, Du, Xinhua, Yu, Xionghui, Jiang, Qian, Zheng, Kaiwen, Xu, Jinzhong, Wang, Pinmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225448/ https://www.ncbi.nlm.nih.gov/pubmed/35736144 http://dx.doi.org/10.3390/md20060341

Ejemplares similares

Recent Advances in Strategies for the Cloning of Natural Product Biosynthetic Gene Clusters
por: Wang, Wenfang, et al.
Publicado: (2021)

An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters
por: Hao, Tingting, et al.
Publicado: (2019)

Heterologous production of fungal natural products: Reconstitution of biosynthetic gene clusters in model host Aspergillus oryzae
por: OIKAWA, Hideaki
Publicado: (2020)

Cloning and Heterologous Expression of a Large-sized Natural Product Biosynthetic Gene Cluster in Streptomyces Species
por: Nah, Hee-Ju, et al.
Publicado: (2017)

Cloning of the Bisucaberin B Biosynthetic Gene Cluster from the Marine Bacterium Tenacibaculum mesophilum, and Heterologous Production of Bisucaberin B
por: Fujita, Masaki J., et al.
Publicado: (2018)

Cloning, Characterization and Heterologous Expression of the Indolocarbazole Biosynthetic Gene Cluster from Marine-Derived Streptomyces sanyensis FMA
por: Li, Tong, et al.
Publicado: (2013)

Cloning and Heterologous Expression of the Grecocycline Biosynthetic Gene Cluster
por: Bilyk, Oksana, et al.
Publicado: (2016)

Identification and heterologous expression of the globomycin biosynthetic gene cluster
por: Oves-Costales, Daniel, et al.
Publicado: (2023)

Novel indole diketopiperazine stereoisomers from a marine-derived fungus Aspergillus sp
por: Li, Xinyang, et al.
Publicado: (2022)

A computational workflow for the expansion of heterologous biosynthetic pathways to natural product derivatives
por: Hafner, Jasmin, et al.
Publicado: (2021)

Presence, Mode of Action, and Application of Pathway Specific Transcription Factors in Aspergillus Biosynthetic Gene Clusters
por: Wang, Wenjie, et al.
Publicado: (2021)

Recent Advances in the Discovery and Biosynthetic Study of Eukaryotic RiPP Natural Products
por: Luo, Shangwen, et al.
Publicado: (2019)

Transcription Factor Repurposing Offers Insights into Evolution of Biosynthetic Gene Cluster Regulation
por: Wang, Wenjie, et al.
Publicado: (2021)

Heterologous Synthesis of Monacolin J by Reconstructing Its Biosynthetic Gene Cluster in Aspergillus niger
por: Zeng, Xu, et al.
Publicado: (2022)

Heterologous Expression of Pseudouridimycin and Description of the Corresponding Minimal Biosynthetic Gene Cluster
por: Böhringer, Nils, et al.
Publicado: (2021)

Methylthio-Aspochalasins from a Marine-Derived Fungus Aspergillus sp.
por: Liu, Ying, et al.
Publicado: (2014)

Simple and rapid direct cloning and heterologous expression of natural product biosynthetic gene cluster in Bacillus subtilis via Red/ET recombineering
por: Liu, Qingshu, et al.
Publicado: (2016)

Heterologous Expression of Ilicicolin H Biosynthetic Gene Cluster and Production of a New Potent Antifungal Reagent, Ilicicolin J
por: Lin, Xiaojing, et al.
Publicado: (2019)

Multiplying the heterologous production of spinosad through tandem amplification of its biosynthetic gene cluster in Streptomyces coelicolor
por: Li, Hong, et al.
Publicado: (2021)

Heterologous Expression of the Formicamycin Biosynthetic Gene Cluster Unveils Glycosylated Fasamycin Congeners
por: McDonald, Hannah P., et al.
Publicado: (2023)

Discovery, Bioactivity Evaluation, Biosynthetic Gene Cluster Identification, and Heterologous Expression of Novel Albofungin Derivatives
por: She, Weiyi, et al.
Publicado: (2021)

Recent Advances in the Discovery and Development of Marine Microbial Natural Products
por: Xiong, Zhi-Qiang, et al.
Publicado: (2013)

Pseudobulbiferamides: Plasmid-Encoded Ureidopeptide Natural Products with Biosynthetic Gene Clusters Shared Among Marine Bacteria of Different Genera
por: Zhong, Weimao, et al.
Publicado: (2023)

Heterologous expression of Avermectins biosynthetic gene cluster by construction of a Bacterial Artificial Chromosome library of the producers
por: Deng, Qian, et al.
Publicado: (2017)

Heterologous Production in the Synechocystis Chassis Suggests the Biosynthetic Pathway of Astaxanthin in Cyanobacteria
por: Liang, Hanyu, et al.
Publicado: (2023)

Heterologous expression of pikromycin biosynthetic gene cluster using Streptomyces artificial chromosome system
por: Pyeon, Hye-rim, et al.
Publicado: (2017)

Bioprospecting Through Cloning of Whole Natural Product Biosynthetic Gene Clusters
por: Lin, Zhenquan, et al.
Publicado: (2020)

An Isotopic Labeling Approach Linking Natural Products with Biosynthetic Gene Clusters
por: McCaughey, Catherine S., et al.
Publicado: (2022)

Expression of fungal biosynthetic gene clusters in S. cerevisiae for natural product discovery
por: Liu, Zihe, et al.
Publicado: (2021)

Recent Advances and Applications of Experimental Technologies in Marine Natural Product Research
por: Li, Ke, et al.
Publicado: (2015)

Recent Advances of Marine Natural Indole Products in Chemical and Biological Aspects
por: Sun, Haoyi, et al.
Publicado: (2023)

Comparative Genomic Insights into Secondary Metabolism Biosynthetic Gene Cluster Distributions of Marine Streptomyces
por: Xu, Lin, et al.
Publicado: (2019)

Recent Advances in Strategies for Activation and Discovery/Characterization of Cryptic Biosynthetic Gene Clusters in Streptomyces
por: Nguyen, Chung Thanh, et al.
Publicado: (2020)

Genetic engineering and heterologous expression of the disorazol biosynthetic gene cluster via Red/ET recombineering
por: Tu, Qiang, et al.
Publicado: (2016)

New Polyketides from the Marine-Derived Fungus Letendraea Sp. 5XNZ4-2
por: Xu, Yan, et al.
Publicado: (2019)

Genome mining for natural product biosynthetic gene clusters in the Subsection V cyanobacteria
por: Micallef, Melinda L., et al.
Publicado: (2015)

Identification of a Pantoea Biosynthetic Cluster That Directs the Synthesis of an Antimicrobial Natural Product
por: Walterson, Alyssa M., et al.
Publicado: (2014)

Phylogenetic classification of natural product biosynthetic gene clusters based on regulatory mechanisms
por: Rodriguez-Sanchez, Alberto C., et al.
Publicado: (2023)

The Sound of Silence: Activating Silent Biosynthetic Gene Clusters in Marine Microorganisms
por: Reen, F. Jerry, et al.
Publicado: (2015)

Upregulation of a marine fungal biosynthetic gene cluster by an endobacterial symbiont
por: Shao, Mingwei, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_n32a4j200oc5p1e5cb6c81e2au